Research Note: Integrative analysis of transcriptome and gut microbiome reveals foie gras capacity difference between cage and floor rearing systems.

To explore the differences in foie gras performance between geese raised in cages and on the ground, we conducted an integrative analysis of liver transcriptome and gut microbial metagenomes. The results showed extremely significant differences in the liver weight (P < 0.01) and liver lipid accumulation of FRS and CRS groups.

Innovative Approach to Chiral Polyurethanes: Asymmetric Copolymerization with Isocyanates.

The introduction of nitrogen-containing functional groups to chiral polymer backbones enables the tailoring of physical properties and offers opportunities for further post-polymerization modification. However, the substrate scope of such polymers is extremely limited because monomers having nitrogen-containing groups can change coordination state with respect to the metal centers, thus decreasing the activity and enantioselectivity and even poisoning the catalyst completely. In this paper, we report our attempts to carry out the asymmetric copolymerization of meso-epoxide with highly reactive isocyanates.

Multi-omics reveals goose fatty liver formation from metabolic reprogramming.

To comprehensively provide insight into goose fatty liver formation, we performed an integrative analysis of the liver transcriptome, lipidome, and amino acid metabolome, as well as peripheral adipose tissue transcriptome analysis using samples collected from the overfed geese and normally fed geese. Transcriptome analysis showed that liver metabolism pathways were mainly enriched in glucolipid metabolism, amino acid metabolism, inflammation response, and cell cycle; peripheral adipose tissue and the liver cooperatively regulated liver lipid accumulation during overfeeding. Liver lipidome patterns obviously changed after overfeeding, and 157 different lipids were yielded.

Electroreductive Ring-Opening Carboxylation of 1,3-Oxazolidin-2-ones with CO for Accessing β-Amino Acids.

Electrocarboxylation of the C(sp)-O bond in 1,3-oxazolidin-2-ones with CO to achieve β-amino acids is developed. The C-O bond in substrates can be selectively cleaved via the single electron transfer on the surface of a cathode or through a CO  intermediate under additive-free conditions. A great diversity of β-amino acids can be obtained in a moderate to excellent yield and readily converted to various biologically active compounds.

Integrative analysis of transcriptome and lipidome reveals fructose pro-steatosis mechanism in goose fatty liver.

To further explore the fructose pro-steatosis mechanism, we performed an integrative analysis of liver transcriptome and lipidome as well as peripheral adipose tissues transcriptome analysis using samples collected from geese overfed with maize flour (control group) and geese overfed with maize flour supplemented with 10% fructose (treatment group). Overfeeding period of the treatment group was significantly shorter than that of the control group ( < 0.05).

Lipidomics analysis reveals new insights into the goose fatty liver formation.

Our previous study described the mechanism of goose fatty liver formation from cell culture and transcriptome. However, how lipidome of goose liver response to overfeeding is unclear. In this study, we used the same batch of geese (control group and corn flour overfeeding group) to explore the lipidome changes and underlying metabolic mechanisms of goose fatty liver formation.

Influence of different types of sugar on overfeeding performance-part of meat quality.

Previous research in our lab showed that 10% glucose, 10% fructose, and 10% sucrose can induce lipid deposition in goose fatty liver formation process more efficiently. However, whether the overfeeding diet supplement with sugar can affect the meat quality is unclear. The aim of this research was to estimate the meat quality of geese overfed with overfeeding diet adding with different types of sugar.

Study on the effect of different types of sugar on lipid deposition in goose fatty liver.

Early research in our lab indicated that the effect of glucose, fructose and sucrose on the levels of triacylglycerol, and inflammatory factor was significantly different, and it is speculated that the regulatory mechanism of lipid deposition by different type of sugar in the liver is different. In order to explore lipid deposition difference mediated by different types of sugar (glucose, fructose, and sucrose) in goose fatty liver formation, this experiment was performed from cell culture, overfeeding experiment, and transcriptome analysis at 3 levels. Cell culture experiment results indicated that the levels of intracellular triglyceride, total cholesterol, and lipid content of fructose and sucrose treatment were significantly higher than those of glucose treatment (P < 0.

Pitaya-like carbon-coated ZnS/carbon nanospheres with inner three-dimensional nanostructure as high-performance anode for lithium-ion battery.

The electrochemical performance of ZnS-based anode materials for Li-ion storage is far from satisfactory due to the incomplete protection of carbon against the volume change. To address this issue, we synthesized a pitaya-like carbon-coated ZnS/carbon nanosphere with rich mesopores (denoted as ZnS/C@C) that can be a promising anode material for Li-ion storage. ZnS/C@C were synthetized via a facile hydrothermal method followed by a chemical vapor deposition process.

Hydrogen bond-assisted synthesis of MoS/reduced graphene oxide composite with excellent electrochemical performances for lithium and sodium storage.

MoS/reduced graphene oxide composites (MoS/rGO) were successfully prepared by a designed tris(hydroxymethyl)methyl aminomethane (named THAM)-assisted hydrothermal method, which involves the modification of THAM on the surfaces of graphene oxide via hydrogen bonds and then the adsorption of MoO on the decorated surfaces due to the electrostatic attraction. The three-dimensional framework of interconnected rGO nanosheets provides good electronic conductivity and facile strain release during the electrochemical reaction, thus enhancing the overall performance of the MoS-based electrode. Herein, the composite delivers high specific capacity, excellent cycling stability and rate performance for lithium- and sodium- ions batteries (LIBs and SIBs).

(101) Plane-Oriented SnS Nanoplates with Carbon Coating: A High-Rate and Cycle-Stable Anode Material for Lithium Ion Batteries.

Tin disulfide is considered to be a promising anode material for Li ion batteries because of its high theoretical capacity as well as its natural abundance of sulfur and tin. Practical implementation of tin disulfide is, however, strongly hindered by inferior rate performance and poor cycling stability of unoptimized material. In this work, carbon-encapsulated tin disulfide nanoplates with a (101) plane orientation are prepared via a facile hydrothermal method, using polyethylene glycol as a surfactant to guide the crystal growth orientation, followed by a low-temperature carbon-coating process.

MoS2 Nanosheets Vertically Grown on Graphene Sheets for Lithium-Ion Battery Anodes.

A designed nanostructure with MoS2 nanosheets (NSs) perpendicularly grown on graphene sheets (MoS2/G) is achieved by a facile and scalable hydrothermal method, which involves adsorption of Mo7O24(6-) on a graphene oxide (GO) surface, due to the electrostatic attraction, followed by in situ growth of MoS2. These results give an explicit proof that the presence of oxygen-containing groups and pH of the solution are crucial factors enabling formation of a lamellar structure with MoS2 NSs uniformly decorated on graphene sheets. The direct coupling of edge Mo of MoS2 with the oxygen from functional groups on GO (C-O-Mo bond) is proposed.