Identification of IspD as a novel target for tuberculosis treatment using compound M6.

Introduction: Tuberculosis (TB) is a serious infectious disease that endangers human health, and TB becomes more difficult in eradiation due to its multidrug resistance (MDR). The objective of this research was to identify novel targets for treating TB.

Methods: A 2-fold serial dilution method was used to determine minimal inhibitory concentrations (MIC) of compound M6 against ().

Behavioural strategies of manufacturing firms for high-quality development from the perspective of government participation: A three-part evolutionary game analysis.

The high-quality development of the manufacturing industry is not only a requirement of industrial transformation and upgrading but also an internal task for the sustainable development of manufacturing enterprises. The high-quality development of the manufacturing industry is a process of multi-participation and dynamic evolution. To understand the evolution of the high-quality development of the manufacturing industry, an evolutionary game model composed of local governments, leading enterprises, and following enterprises is constructed.

Familiarity ratings for 24,325 simplified Chinese words.

The present work collected familiarity norms for 20,275 two-character, 1231 three-character, and 2819 four-character simplified Chinese words from 1300 native speakers of Mandarin Chinese. The familiarity of each word was rated on a 7-point scale by at least 21 participants. The results supported the reliability and validity of the present familiarity ratings, which is the first large familiarity database for Chinese in the field.

Interaction effects of aging, word frequency, and predictability on saccade length in Chinese reading.

Background: It was well known that age has an impact on word processing (word frequency or predictability) in terms of fixating time during reading. However, little is known about whether or not age modulates these impacts on saccade behaviors in Chinese reading (i.e.

[Analysis on the relationship between malaria epidemics and NOAA-AVHRR NDVI in Hainan province].

Objective: To explore the relationship between malaria epidemics and NOAA-AVHRR NDVI.

Methods: Data on malaria were collected in all 19 counties in Hainan province from Feb, 1995 to Jan, 1996. Values regarding normalized difference vegetation index (NDVI)-related indicators including mean and maximum values of NDVI, the area proportion of NDVI values of 145- and 145+, months with NDVI values of 135+, 140+, 145+, 150+ of these counties in this period were all extracted from NOAA-AVHRR images, using ERDAS8.

[Study on the distribution of malaria in Hainan province through spatial local interpolation technique].

Objective: To explore the spatial distribution of malaria in Hainan province.

Methods: Maps of spatial distribution on malaria incidence in Hainan province from 1995 to 1999 were produced, using a spatial local interpolation technique in the ArcGIS 8.1 software.