Publications by authors named "Yongqiang Lao"
An acid-promoted cyclization of α-azidobenzyl ketones has been developed for the synthesis of 6-substituted quinoline derivatives. A variety of synthetically useful 6-OTf or -OMs quinoline derivatives were obtained in moderate to good yields. The reaction proceeds via C═N bond formation without organophosphine, providing convenient access to structurally interesting and synthetically important 6-substituted quinoline derivatives in moderate to good yields.
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- - Giant cell angioblastoma is a rare vascular tumor with limited studies on its clinical and imaging characteristics, featuring four reported cases involving male patients of varying ages with lesions primarily in the femur and knee area.
- - Imaging showed either bone destruction or soft tissue invasion, with histopathology revealing nodular tissue composed of spindle-shaped cells and multinucleated giant cells, alongside specific cell markers identified through immunophenotyping.
- - Treatment generally involves surgical resection, with one case experiencing a relapse, but there were no instances of distant metastasis or death during follow-up, suggesting it is a locally invasive tumor manageable through surgery and potentially interferons.
Background And Objectives: To compare mechanical properties of femoral tumor treatments so that better operative strategy for limb tumors surgery is optimized.
Methods: Fourteen femoral CT images were randomly selected to rebuild 3D models by MIMICS. They were then executed by reverse engineering softwares for simulative modes.