Research Advances in Marine Aquaculture Net-Cleaning Robots.

In the realm of marine aquaculture, the netting of cages frequently accumulates marine fouling, which impedes water circulation and poses safety hazards. Traditional manual cleaning methods are marked by inefficiency, high labor demands, substantial costs, and considerable environmental degradation. This paper initially presents the current utilization of net-cleaning robots in the cleaning, underwater inspection, and monitoring of aquaculture cages, highlighting their benefits in enhancing operational efficiency and minimizing costs.

YTHDF1 regulates GID8-mediated glutamine metabolism to promote colorectal cancer progression in m6A-dependent manner.

Dysregulation of epigenetics is a hallmark of cancer development, and YTHDF1 stands out as a crucial epigenetic regulator with the highest DNA copy number variation among all N6-methyladenosine (m6A) regulators in colorectal cancer (CRC) patients. Here, we aimed to investigate the specific contribution of YTHDF1 overexpression to CRC progression and its consequences. Through multiple bioinformatic analyses of human cancer databases and clinical CRC samples, we identified GID8/Twa1 as a crucial downstream target of YTHDF1.

Optimization Strategy for Formaldehyde Removal by Carbon Cathode Electro-Fenton: Enhancement of Formaldehyde and Oxygen Co-adsorption by Rational Nitrogen Doping Types.

This study investigates the effect of N-doped coal-based activated carbon cathode on formaldehyde-oxygen coadsorption. Further investigation investigates the effect of formaldehyde-oxygen coadsorption on HO generation and formaldehyde removal in an electro-Fenton system. Nitrogen doping enhances formaldehyde and oxygen coadsorption by modulating competitive adsorption.

Evaluation of agricultural non-point source pollution using an in-situ and automated photochemical flow analysis system.

Off-line leachate collection from agricultural landscapes cannot guarantee precise evaluation of agricultural non-point source (ANPS) due to geospatial variations, time, and transportation from the field to the laboratory. Implementing an in-situ nitrogen and phosphorous monitoring system with a robust photochemical flow analysis is imperative for precision agriculture, enabling real-time intervention to minimize non-point source pollution and overcome the limitations posed by conventional analysis in laboratory. A reliable, robust and in-situ approach was proposed to monitor nitrogen and phosphorous for determining ANPS pollution.

Mechanisms of efficient indoor formaldehyde removal via electro-Fenton: Synergy in ·OH generation and utilization through a modified carbon cathode.

Indoor formaldehyde poses a significant carcinogenic risk to human health, making its removal imperative. Electro-Fenton degradation has emerged as a promising technology for addressing this concern. In the electro-Fenton system, ·OH is identified as the primary active species responsible for formaldehyde removal.

Success rate of current human-derived gastric cancer organoids establishment and influencing factors: A systematic review and meta-analysis.

Background: Human-derived gastric cancer organoids (GCOs) are widely used in gastric cancer research; however, the culture success rate is generally low.

Aim: To explore the potential influencing factors, and the literature on successful culture rates of GCOs was reviewed using meta-analysis.

Methods: PubMed, Web of Science, and EMBASE were searched for studies.

Topological Defect-Regulated Porous Carbon Anodes with Fast Interfacial and Bulk Kinetics for High-Rate and High-Energy-Density Potassium-Ion Batteries.

Carbonaceous materials are regarded as one of the most promising anodes for potassium-ion batteries (PIBs), but their rate capabilities are largely limited by the slow solid-state potassium diffusion kinetics inside anode and sluggish interfacial potassium ion transfer process. Herein, high-rate and high-capacity PIBs are demonstrated by facile topological defect-regulation of the microstructure of carbon anodes. The carbon lattice of the as-obtained porous carbon nanosheets (CNSs) with abundant topological defects (TDPCNSs) holds relatively high potassium adsorption energy yet low potassium migration barrier, thereby enabling efficient storage and diffusion of potassium inside graphitic layers.

Maturity Classification of Rapeseed Using Hyperspectral Image Combined with Machine Learning.

Oilseed rape is an important oilseed crop planted worldwide. Maturity classification plays a crucial role in enhancing yield and expediting breeding research. Conventional methods of maturity classification are laborious and destructive in nature.

Traditional Chinese medicine Qingre Huoxue decoction enhances wound healing in through modulation of angiogenic and inflammatory pathways.

This study investigates the therapeutic potential of Qingre Huoxue Decoction (QHD), a traditional Chinese herbal formulation, in promoting wound healing in an imiquimod-induced murine model of psoriasis. The research was driven by the need for effective wound healing strategies in psoriatic conditions, where conventional treatments often fall short. Employing a combination of in vivo and in vitro methodologies, we assessed the effects of QHD on key factors associated with wound healing.

Development and characterization of anti-IL-5 monoclonal antibody Fab fragment for blocking IL-5/IL-5Rα binding.

Interleukin-5 (IL-5) is a homodimeric cytokine that is a crucial regulator of the proliferation, activation, and maturation of eosinophils. Anti-IL-5 monoclonal antibodies, which block the binding of IL-5 to the IL-5 receptor subunit alpha (IL-5Rα), have been successfully used to treat eosinophilic (EOS) asthma. The currently marketed monoclonal antibody drugs require repeated injections for administration, which seriously affect patient compliance and high systemic exposure for injectable drug delivery.

Visual prior-based cross-modal alignment network for radiology report generation.

Automated radiology report generation is gaining popularity as a means to alleviate the workload of radiologists and prevent misdiagnosis and missed diagnoses. By imitating the working patterns of radiologists, previous report generation approaches have achieved remarkable performance. However, these approaches suffer from two significant problems: (1) lack of visual prior: medical observations in radiology images are interdependent and exhibit certain patterns, and lack of such visual prior can result in reduced accuracy in identifying abnormal regions; (2) lack of alignment between images and texts: the absence of annotations and alignments for regions of interest in the radiology images and reports can lead to inconsistent visual and textual features of the abnormal regions generated by the model.

Does financial globalization promote renewable energy investment? Empirical insights from China.

The increasing integration of financial markets worldwide has brought about significant changes in the investment landscape for renewable energy. However, the connection between financial globalization and renewable energy investment has gotten relatively little consideration. As a result, the analysis's main goal is to determine the asymmetric nexus between financial globalization and renewable energy investment in China, covering the period from 1995 to 2021.

Economic Growth, Income Inequality and Food Safety Risk.

Food safety risk, as an implicit cost of social and economic development, endangers the health of global residents, including China. To systematically understand the impact of socioeconomic development on food safety risk and to establish a sound modern governance system of food safety in China, this paper uses provincial panel data from 2011 to 2020 to explore the relationship between food safety risk and socio-economic development factors such as economic growth and income inequality by employing a two-way fixed effect model and moderating effect model. The results show that the food safety risk is a Kuznets curve, and the turning point is about RMB 58,104.

Association of working hours and cumulative fatigue among Chinese primary health care professionals.

Introduction: The association between long working hours and cumulative fatigue is widely acknowledged in the literature. However, there are few studies on the mediating effect of working hours on cumulative fatigue using occupational stress as a mediating variable. The present study aimed at investigating the mediating role of occupational stress in the relationship between working hours and cumulative fatigue in a sample of 1,327 primary health care professionals.

Rapid and Sensitive Detection of Polycyclic Aromatic Hydrocarbons in Tea Leaves Using Magnetic Approach.

A rapid and efficient method using an alkyl-functionalized magnetic nanoparticles-based extraction technique combined with Ultra-High Performance Liquid Chromatography was developed for the detection of trace amounts of polycyclic aromatic hydrocarbons in tea leaves. As a popular coating for chromatographic column packing materials, C-alkyl has been demonstrated to be effective in separating polycyclic aromatic hydrocarbons. Additionally, the magnetism of the nanomaterials accelerates the extraction process while their high surface ratio enables desirable dispersity in the sample matrix.

Pseudocapacitive Potassium-Ion Intercalation Enabled by Topologically Defective Soft Carbon toward High-Rate, Large-Areal-Capacity, and Low-Temperature Potassium-Ion Batteries.

Carbonaceous materials are widely investigated as anodes for potassium-ion batteries (PIBs). However, the inferior rate capability, low areal capacity, and limited working temperature caused by sluggish K-ions diffusion kinetics are still primary challenges for carbon-based anodes. Herein, a simple temperature-programmed co-pyrolysis strategy is proposed for the efficient synthesis of topologically defective soft carbon (TDSC) based on inexpensive pitch and melamine.

Construction and analysis of a nomogram prediction model for post-infectious bronchiolitis obliterans in children with adenovirus pneumonia after invasive mechanical ventilation.

Background: Post-infectious bronchiolitis obliterans (PIBO) is the most common sequelae in children with adenovirus pneumonia (ADVP). However, there are few studies on the risk factors for PIBO occurrence. This study aims to investigate the risk factors for PIBO in pediatric patients with severe ADVP, especially after invasive mechanical ventilation (IMV), as well as to build a nomogram prediction model.

Preparation and antibacterial and antioxidant ability of β-cyclodextrin complexes of vaporized essential oil.

Compared with traditional liquid-liquid embedding method and solid-liquid embedding method of inclusion complexes of β-cyclodextrin (β-CD) inclusion of essential oil to form stable properties, the gas-liquid embedding method was applied to encapsulate vaporized essential oil (IvEO), with β-CD as wall materials so that core and wall materials molecules are in active state during complexing process. At optimal conditions with a mass ratio of 1:10, temperature of 80°C, time of 1 h, the β-CD-IvEO inclusion complexes (β-CD-IvEO-ICs) had an encapsulation efficiency (EE) of 84.55 ± 2.

Predictive Value of Adenoviral Load for Bronchial Mucus Plugs Formation in Children with Adenovirus Pneumonia.

Background: The study aimed to explore risk factors for bronchial mucus plugs (BMP) formation in children with adenovirus (AdV) pneumonia.

Methods: A retrospective study was conducted on children with AdV pneumonia who underwent bronchoscopy from January 2019 to December 2019. Children were divided into the BMP group and the control group, depending on whether BMP was formed or not.

Advances in the Study of Inhaled Formulations for the Treatment of Pulmonary Arterial Hypertension.

Pulmonary arterial hypertension (PAH) is a serious disease with reduced systemic circulation and low bioavailability associated with conventional and dosed therapy, which inhaled drugs can avoid. A mean pulmonary artery pressure (mPAP) of ≥25 mmHg (1 mmHg = 0.133 kPa) at rest or ≥30 mmHg during exercise and a pulmonary capillary pressure or left atrial pressure (PLA) of ≤15 mmHg can be diagnosed with PAH.

Efficacy and safety of Elian Granules in treating chronic atrophic gastritis: study protocol for a randomized, double-blind, placebo-controlled, multicenter clinical trial.

Background: Multifocal atrophic gastritis and intestinal metaplasia are considered to be important links in the gastric precancerous cascade. However, there are no specific drugs for these conditions. Although many studies have shown that traditional Chinese medicine is effective with no serious side effects, these studies have not been scientifically rigorous trials.