Publications by authors named "Yongnian Zhang"

Plant wearable sensors have shown exceptional promise in continuously monitoring plant health. However, the potential adverse effects of these sensors on plant growth remain unclear. This study systematically quantifies wearable sensors' interference with plant growth using two ornamental species, and .

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Article Synopsis
  • Colorectal cancer (CRC) is a common type of cancer in the intestines and is the second leading cause of these tumors.
  • Special tests can look at gut bacteria from CRC patients, helping to find important clues about this cancer.
  • Some bacteria can help tumors grow and may cause cancer by releasing harmful toxins, so understanding these bacteria might help in stopping or treating CRC.
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Background: Colon cancer (CC) is a malignant tumor with a high incidence and poor prognosis. Accumulating evidence shows that the immune signature plays an important role in the tumorigenesis, progression, and prognosis of CC. Our study is aimed at establishing a novel robust immune-related gene pair signature for predicting the prognosis of CC.

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By integrating multiple remote sensing data sources this study accurately assesses the spatiotemporal characteristics of changes in ecosystem service values (ESVs) in the Yellow River Basin from 2000 to 2015 through Theil-Sen median trend analysis and the Mann-Kendall test. The stability and continuity of the ESVs were comprehensively characterized using coefficients of variation and the Hurst exponent. The degree of coherence between ESVs and economic growth (represented by gross domestic product GDP) on the same temporal and spatial scales was analyzed using ecological-economic coordination (EEC) models.

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We described 4 human infection cases of zoonotic fish-tapeworm, , identified with morphological and molecular characters and briefly reviewed Chinese cases in consideration of it as an emerging parasitic disease in China. The scolex and mature and gravid proglottids of some cases were seen, a rosette-shaped uterus was observed in the middle of the mature and gravid proglottids, and the diphyllobothriid eggs were yellowish-brown in color and displayed a small knob or abopercular protuberance on the opposite end of a lid-like opening. The average size of the eggs was recorded as 62-6742-45 μm.

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Objective: To analyze the results of parasitic pathogen detection on clinical samples from Shanghai hospitals during 2011-2013.

Methods: Samples of serum, stool, sputum, body fluid and biopsy were collected from hospitals. The etiological, serological and molecular biology methods were used to detect parasitic infection cases.

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The cause of diphyllobothriosis in 5 persons in Harbin and Shanghai, China, during 2008-2011, initially attributed to the tapeworm Diphyllobothrium latum, was confirmed as D. nihonkaiense by using molecular analysis of expelled proglottids. The use of morphologic characteristics alone to identify this organism was inadequate and led to misidentification of the species.

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Background: Food-borne helminthiases (FBHs) have become increasingly important due to frequent occurrence and worldwide distribution. There is increasing demand for developing more sensitive, high-throughput techniques for the simultaneous detection of multiple parasitic diseases due to limitations in differential clinical diagnosis of FBHs with similar symptoms. These infections are difficult to diagnose correctly by conventional diagnostic approaches including serological approaches.

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Objective: To inspect the third stage larvae of Gnathostoma in imported Monopterus albus, and identify its species.

Methods: Ten batches of M. albus imported to Shanghai were detected for nematode Gnathostoma from January 2010 to March 2011.

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[One case of breast sparganosis mansoni].

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi

February 2011

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Objective: To observe the in vitro effect of praziquantel, tribendimidine, levamisole, artemether, artesunate, albendazole and mebendazole against adult Clonorchis sinensis.

Methods: Seventy rats infected with 50-100 C. sinensis metacercariae for 5-7 weeks were euthanized, and adult C.

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Angiostrongylus cantonensis causes eosinophilic meningitis and eosinophilic pleocytosis in humans and is of significant socio-economic importance globally. microRNAs (miRNAs) are endogenous small non-coding RNAs that play crucial roles in gene expression regulation, cellular function and defense, homeostasis and pathogenesis. They have been identified in a diverse range of organisms.

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Objective: To observe the effect of praziquantel, mebendazole, tribendimidine, ivermectin, artemether and dihydroartemisinin against Armillifer agkistrodontis nymphs harbored in mice.

Method: Thirty-five mice infected each with 40 eggs of Armillifer agkistrodontis for 25-37 weeks were divided into 10 groups (2-8 mice per group). Among them, nine groups were treated orally with praziquantel 500 mg/(kg x d) x 5 d or 500 my/(kg x d) x 14 d, mebendazole 300 mg/(kg x d)x 5 d, tribendimidine 300 mg/(kg x d) x 5 d, ivermectin 8-10 mg/(kg x d) x 3 d or 15 mg/(kg x d) x l4 d, artemether 400 mg/(kg x d) x 5 d and dihydroartemisinin 200 mg/(kg x d) x 5 d, respectively.

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The aim of the study is to understand the anti-Clonorchis sinensis properties of mebendazole and albendazole, and compare to praziquantel and tribendimidine. Two hundred and thirty rats were divided into five batches for experimental treatment. In four batches, each rat was infected orally with 50 or 100 C.

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Objective: To evaluate the efficacy in treatment of Clonorchis sinensis-infected rats using the administration regimens of tribendimidine, artesunate and praziquantel applied in clinical treatment of clonorchiasis.

Methods: The doses of tribendimidine, artesunate and praziquantel used in clinical treatment of clonorchiasis were converted to the doses used in rats by the method of equal effective dose conversion among different animals, while the administration regimens of the drugs were designed basing on the regimens used in clinical trials. Thus, the following dose schedules were set up, i.

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The aim of the study is to explore the effect of mefloquine against Clonorchis sinensis and Paragonimus westermani. For anti-C. sinensis study, a total of 71 rats were divided into four batches for oral infection of each rat with 50 C.

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Objective: To observe the efficacy of tribendimidine and albendazole against Trichinella spiralis in mice.

Methods: A total of 85 Kunming strain mice, infected orally with 100 T. spiralis larvae, was divided into 3 groups: group A (adult stage, 7 d after infection), group B (migrating larva stage, 15 d after infection), and group C (encapsulated larva stage, 35 d after infection).

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Background: Pentastomiasis is a rare parasitic infection of humans. Pentastomids are dioecious obligate parasites requiring multiple hosts to complete their lifecycle. Despite their worm-like appearance, they are commonly placed into a separate sub-class of the subphylum Crustacea, phylum Arthropoda.

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Objective: To observe the effect of tribendimidine, artesunate and praziquantel in treatment of hamsters (Mesocricetus auratus) infected with Clonorchis sinensis.

Methods: A total of 93 hamsters, each infected with 30 C. sinensis metacercariae, were treated intragastrically with above-mentioned drugs at a single dose.

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The purpose of the study was to understand the in vitro and in vivo effect of tribendimidine (TBD) and its metabolites of p-(1-dimethylamino ethylimino)aniline (aminoamidine, deacylated amidantel, BAY d 9216, dADT), acetylated dADT (AdADT), terephthalaldehyde (TPAL), and terephthalic acid (TPAC) against adult Clonorchis sinensis. In in vitro test, the adults of C. sinensis were placed to each of the 24 wells of a Falcon plate and maintained in Hanks' balanced salt solution-20% calf serum.

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Objective: To assess the efficacy of single, multiple or combined oral doses of tribendimidine, artesunate, artemether and praziquantel against Clonorchis sinensis in rats.

Methods: A total of 147 rats, each infected with 50 C. sinensis metacercariae, were used in experimental chemotherapy.

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