Publications by authors named "Yongmoo Kim"

Purpose: Febrile seizures at a young age can provoke late-onset temporal lobe epilepsy. Since recent evidence has suggested that the gut microbiome affects central nervous system pathology across the blood-brain barrier, we hypothesized that febrile seizures alter the composition of the gut microbiome to provoke epilepsy.

Methods: Third-generation C57BL/6 mice were separated into two groups (n = 5 each), and hot air was applied to only one group to cause febrile seizures.

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Article Synopsis
  • Several cases of MOG antibody-associated encephalitis have been linked to COVID-19 infections, with one patient experiencing severe neurological symptoms post-COVID-19.
  • The patient's symptoms included focal status epilepticus, auditory hallucinations, and incoherent speech, but brain imaging showed no specific abnormalities.
  • Diagnosis was confirmed through cerebrospinal fluid analysis and specific antibody testing, leading to treatment with immunotherapy drugs like intravenous immunoglobulin and rituximab.
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Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection due to reactivation of John Cunningham virus (JCV). The diagnosis depends on evidence from clinical, imaging, and virologic studies. When the cerebrospinal fluid shows a negative polymerase chain reaction result, brain biopsy is required to confirm the diagnosis.

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