Publications by authors named "Yongmei Tu"
Article Synopsis
- * Alpha-1 antitrypsin (α1-AT), a protease inhibitor used for emphysema, has been shown to have anti-inflammatory properties and may help treat phosgene-induced ALI.
- * The study found that α1-AT is produced by neutrophils in response to phosgene exposure and that administering α1-AT can reduce inflammation and cell death by activating a protective mechanism involving the ID1 gene.
Irisin is an exercise-induced myokine that alleviates inflammation and obesity. The induction of anti-inflammatory (M2) macrophage is facilitated for treatment of sepsis and associated lung damage. However, whether irisin drives macrophage M2 polarization remains unclear.
View Article and Find Full Text PDFReactive Oxygen Species Bridge the Gap between Chronic Inflammation and Tumor Development.
Oxid Med Cell Longev
July 2022
According to numerous animal studies, adverse environmental stimuli, including physical, chemical, and biological factors, can cause low-grade chronic inflammation and subsequent tumor development. Human epidemiological evidence has confirmed the close relationship between chronic inflammation and tumorigenesis. However, the mechanisms driving the development of persistent inflammation toward tumorigenesis remain unclear.
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