Global trends and current research in post-traumatic osteoarthritis: A bibliometric and visualization analysis from 2010 to 2024.

Background: To investigate global trends and current research on post-traumatic osteoarthritis (PTOA) from 2010 to 2024 using bibliometric and visualization techniques.

Methods: A bibliometric analysis was conducted using data from the Web of Science Core Collection. The study examined publication trends, author contributions, institutional collaborations, keyword co-occurrence, and citation patterns, employing CiteSpace software to analyze key metrics such as publication frequency, centrality, and clustering.

Bergapten prevents lipopolysaccharide mediated osteoclast formation, bone resorption and osteoclast survival.

Purpose: This study was designed to investigate the potential effect of bergapten on lipopolysaccharide (LPS)-mediated osteoclast formation, bone resorption and osteoclast survival in vitro.

Methods: After osteoclast precursor RAW264.7 cells were treated with bergapten (5, 20, 40 μmol/L) for 72 hours in the presence of LPS (100 ng/ml), osteoclastogenesis was identified by tartrate-resistant acid phosphatase (TRAP) staining, and the number of TRAP-positive multinucleated cells [TRAP(+)MNCs] per well were counted.

Genetic study of alcoholism and novel gene expression in the alcoholic brain.

Alcohol dependence may result from neuroadaptation involving alteration of gene expression after long-term alcohol exposure. The systematic study of gene expression profiles of the human alcoholic brain was initiated using the method of polymerase chain reaction (PCR)-differential display and was followed by DNA microarray. To date, more than 100 alcohol-responsive genes have been identified from the frontal cortex, motor cortex and nucleus accumbens of the human brain.

Auditory ERP in extremely premature 5-year-old children.

The aim of this research was to test the hypothesis of a functional impairment in the automatic detection of deviant tones in 141 children born after 25 to 28 weeks of gestational age, as compared to 45 age-matched full-term control children. All of them were assessed at age 5 years 9 months and instructed to listen passively to two different pure tones (1000 vs 1200 Hz; 20 vs 80%) counterbalanced between ears. Rarity was thus defined by specific ear by tone combinations.