Preliminary study on the effect of lumbar axial rotation on bone mineral density measured by DXA and QCT.

Currently, the relationship between axial rotation of the vertebrae and bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) remains controversial. The aim of this study is to quantitatively assess the effect of vertebral rotation on volumetric bone mineral density (v-BMD) and areal bone mineral density (a-BMD), further to propose the corrected strategies. To achieve this, a phantom, which was rotated from 0° to 25° in 5° increments, was utilized.

Construction and validation of a predictive model of mortality of tuberculosis-destroyed lung patients requiring mechanical ventilation: A single-center retrospective cohort study.

The mortality rate for intensive care unit tuberculosis-destroyed lung (TDL) patients requiring mechanical ventilation (MV) remains high. We conducted a retrospective analysis of adult TDL patients requiring MV who were admitted to the intensive care unit of a tertiary infectious disease hospital in Chengdu, Sichuan Province, China from January 2019 to March 2023. Univariate and multivariate COX regression analyses were conducted to determine independent patient prognostic risk factors that were used to construct a predictive model of patient mortality.

ZN-S10 Reforms the Rhizosphere Microbial Community and Enhances Tomato Resistance to TPN.

Tomato pith necrosis (TPN) is a highly destructive disease caused by species of the genus and other bacteria, resulting in a significant reduction in tomato yield. Members of the genus are beneficial microorganisms extensively studied in the rhizosphere. However, in most cases, the potential of members in controlling TPN and their impact on the rhizosphere microbial composition remain rarely studied.

[Source Analysis and Risk Assessment of Heavy Metals in Soil of County Scale Based on PMF Model].

This study explores the pollution characteristics, risks, and sources of heavy metals in small-scale areas. Rongcheng District, Jieyang City, Guangdong Province was considered as the study area and enrichment factor (EF), pollution load index (PLI), potential ecological risk index (RI), and US EPA health risk assessment model were used to evaluate its environmental risk. Moreover, the source apportionment of heavy metals was analyzed through correlation analysis, the characteristic of spatial distribution, and a PMF model.

Performance of Creatinine- and Cystatin C-Based Equations for Glomerular Filtration Rate Estimation in HIV-1-Infected Individuals Receiving Dolutegravir + Tenofovir Disoproxil Fumarate + Lamivudine as Initial Antiretroviral Therapy: A Retrospective Observational Study.

Background: Dolutegravir (DTG) may inhibit organic cation transporter-2 in renal tubules and elevate serum creatinine levels without true renal function deterioration. There are scarce data on the glomerular filtration rate (GFR) equations in Chinese HIV patients with DTG/TDF/3 TC. This retrospective study was to evaluate the changes in creatinine- and cystatin C-based estimated GFR values among Chinese adult HIV patients with initial highly active antiretroviral therapy (HAART) with DTG/TDF/3 TC for 48 weeks.

Visible light-controlled living cationic polymerization of methoxystyrene.

Photo-controlled living polymerization has received great attention in recent years. However, despite the great success therein, the report on photo-controlled living cationic polymerization has been greatly limited. We demonstrate here a novel decolorable, metal-free and visible light-controlled living cationic polymerization system by using tris(2,4-dimethoxyphenyl)methylium tetrafluoroborate as the photocatalyst and phosphate as the chain transfer agent (CTA) for polymerization of 4-methoxystyrene.

Not Only High Number and Specific Comorbidities but Also Age Are Closely Related to Progression and Poor Prognosis in Patients With COVID-19.

Some patients with comorbidities and rapid disease progression have a poor prognosis. We aimed to investigate the characteristics of comorbidities and their relationship with disease progression and outcomes of COVID-19 patients. A total of 718 COVID-19 patients were divided into five clinical type groups and eight age-interval groups.

Transcriptome analysis associated with polysaccharide synthesis and their antioxidant activity in leaves of different developmental stages.

Background: (Batal.) Iljinskaja is a common endemic tree species and used as a Chinese medicine. The main active components in the leaves of this plant are polysaccharides.

Joint Transcriptomic and Metabolic Analysis of Flavonoids in Leaves.

Flavonoids are a class of commonly occurring natural compounds in the plant kingdom with various biological activities. This study compares the content of flavonoids in at different developmental stages to better inform the selection of the optimal picking period. Thus, we analyzed the transcriptome and metabolome of at different developmental stages.

Epidemiological characteristics and clinical features of 32 critical and 67 noncritical cases of COVID-19 in Chengdu.

Background: In December 2019, Wuhan, China, experienced an outbreak of coronavirus (COVID-19). The number of cases has increased rapidly, but information on the clinical characteristics remains limited.

Objectives: This paper describes the epidemiological and clinical characteristics of COVID-19.

Erythrocyte Membrane Cloaked Curcumin-Loaded Nanoparticles for Enhanced Chemotherapy.

In this study, curcumin-loaded porous poly(lactic--glycolic acid) (PLGA) nanoparticles (NPs) were prepared and surface modified with red blood cell membranes (RBCM) to yield biomimetic RBCM-p-PLGA@Cur NPs. The NPs displayed a visible cell-membrane structure at their exterior and had a uniform size of 162 ± 3 nm. In vitro studies showed that drug release from non-porous PLGA NPs was slow and that much of the drug remained trapped in the NPs.

One-pot synthesis of thermosensitive glycopolymers grafted gold nanoparticles and their lectin recognition.

Thermosensitive glucose-functionalized glycopolymers grafted gold nanoparticles (Glyco@GNPs) with good colloidal stability and thermosensitive in aqueous solution were fabricated by reversible addition-fragmentation chain transfer (RAFT) mediated one-pot synthesis. The formation of core-shell morphology with about a 60 nm gold core in diameter and a glycopolymer shell of about 80 nm in thickness was indicated by transmission electron microscopy (TEM). The recognition ability of the Glyco@GNPs toward lectin concannavalin A (Con A) was verified by ultraviolet-visible spectroscopy and dynamic light scattering (DLS).

Prediction value of unmeasurable MR enhancement at early stage after gross-total resection on the survival state of patients with high-grade glioma.

Propose: To explore the value of unmeasurable enhancement pattern of residual cavity in predicting survival at early stage after gross-total resection in high-grade glioma (HGG) patients.

Methods: This retrospective study enrolled consecutive 51 HGG patients with unmeasurable enhancement who underwent gross-total resection followed by concurrent chemoradiotherapy and adjuvant chemotherapy. We evaluated the enhancement patterns of residual cavity on contrast-T1WI made within 1 month after tumor resection (20 ± 3 days).

Increasing FLAIR signal intensity in the postoperative cavity predicts progression in gross-total resected high-grade gliomas.

To evaluate the prognostic value of fluid-attenuated inversion recovery (FLAIR) signal intensity of postoperative cavity on progression free survival (PFS) and overall survival (OS) in patients with high-grade gliomas (HGG). This study retrospectively enrolled 45 consecutive HGG patients. These patients had chemoradiotherapy after gross-total resection of tumors.

Hyperbranched Multiarm Copolymers with a UCST Phase Transition: Topological Effect and the Mechanism.

A novel thermoresponsive hyperbranched multiarm copolymer with a hydrophobic hyperbranched poly[3-ethyl-3-(hydroxymethyl)oxetane] core and many poly(acrylamide- co-acrylonitrile) (P(AAm- co-AN)) arms was for the first time synthesized through a reversible addition-fragmentation chain-transfer polymerization. These copolymers show reversible, sharp, and controlled temperature-responsive phase transitions at the upper critical solution temperature (UCST) in water and electrolyte solution. It is the first report on the hyperbranched copolymers with a UCST transition.

Construction of Light-Harvesting Polymeric Vesicles in Aqueous Solution with Spatially Separated Donors and Acceptors.

This communication describes polymer vesicles self-assembled from hyperbranched polymers (branched polymersomes (BPs)) as scaffolds, conceptually mimicking the natural light-harvesting system in aqueous solution. The system is constructed with hydrophobic 4-chloro-7-nitro-2,1,3-benzoxadiazole (NBD-Cl) as donors encapsulated in the hydrophobic hyperbranched cores of the vesicles and the hydrophilic Rhodamine B (RB) as acceptors incorporated on the surface of the vesicles through the cyclodextrin (CD)/RB host-guest interactions, through which the donors and acceptors are spatially separated to effectively avoid the self-quenching between donors. This vesicular light harvesting system has presented good energy transfer efficiency of about 80% in water, and can be used as the ink to write multiclolor letters.

Designing hierarchical hollow nanostructures of CuMoS for improved hydrogen evolution reaction.

Layered CuMoS, consisting of earth-abundant elements, is regarded as a potential catalyst for the hydrogen evolution reaction (HER). Herein, we demonstrate a CuO-based template strategy to synthesise hierarchical hollow nanostructures of CuMoS. The characterizations reveal that the electrochemically active surface of the hollow CuMoS is largely enhanced, in contrast to the nanosheet or nanoparticle structures.

A srikaya-like light-harvesting antenna based on graphene quantum dots and porphyrin unimolecular micelles.

A novel hybrid light-harvesting antenna with a srikaya-like structure of multi-graphene quantum dots (GQDs) as donors and one porphyrin unimolecular micelle as the acceptor was constructed through electrostatic self-assembly. The constructed antenna showed a high energy transfer efficiency of up to 93.6% and an antenna effect of 7.

Protein-Framed Multi-Porphyrin Micelles for a Hybrid Natural-Artificial Light-Harvesting Nanosystem.

A micelle-like hybrid natural-artificial light-harvesting nanosystem was prepared through protein-framed electrostatic self-assembly of phycocyanin and a four-armed porphyrin star polymer. The nanosystem has a special structure of pomegranate-like unimolecular micelle aggregate with one phycocyanin acceptor in the center and multiple porphyrin donors in the shell. It can inhibit donor self-quenching effectively and display efficient transfer of excitation energy (about 80.