Research progress of autophagy in heart failure.

Heart failure poses a significant threat to global public health within the realm of cardiovascular diseases. Its pathological progression involves various alterations in cardiomyocytes, among which autophagy, a crucial intracellular degradation mechanism, plays a pivotal role. Autophagy facilitates the breakdown of damaged organelles and proteins, thereby maintaining cellular homeostasis.

The effect of the PERMA model-based positive psychological intervention on the quality of life of patients with breast cancer.

Objective: This research focused on exploring the impact of the PERMA model-based positive psychological intervention according to the negative emotions and quality of life of individuals with breast cancer.

Methods: A total of 82 individuals with breast cancer from our hospital were categorized into two groups randomly; the control group and the observation group (41 affected individuals each). The individuals in the control group underwent routine nursing intervention, while the ones in the observation group underwent PERMA nursing as per routine nursing intervention.

[Brief discussion on the characteristics of meridian sinew theory at the early era].

The characteristics of meridian sinew theory at the early era have been collected. It is believed that the running courses and indications of twelve meridian sinew regions in () are closely associated with () and (). Due to the attachment of twelve regular meridians, the development of its own theory is blocked.

[Analysis of the divergent meridians of twelve meridians].

This paper analyzes the problems existing in the current theory of divergent meridian (""), such as the unclear route of divergent meridian, the controversy in the "---" and the lack of in-depth research on the theory of "", clarifies the source and privides insights. The author analyzed the word "" by means of the four proofreading methods combined with philology method to explore the origin of " ". The divergent meridians is the remnant of the original meridians system in the bamboo and silk documents, which was put into the meridians system after being sorted out by doctors.

[Acupuncture combined with opioid drugs on moderate and severe cancer pain: a randomized controlled trial].

Objective: To explore the clinical therapeutic effect of acupuncture combined with opioid drugs on moderate and severe cancer pain.

Methods: A total of 60 patients with cancer were randomized into an observation group and a control group, 30 cases in each group. Oxycodonehydrochloride prolonged-release tablet was taken orally in the control group.

[Analysis of the academic features of the moxibustion of ' physicians].

' acupuncture and moxibustion physicians have a lot of talented people. Their academic theories promote the development of moxibustion theory. - used acupuncture and moxibustion together in clinic, and emphasized reinforcing and reducing method.

[Statistics and analysis on acupuncture and moxibustion projects of the National Natural Science Foundation of China of traditional Chinese medicine universities and colleges in recent 10 years: taking the General Program and National Science Fund for Young Scholars as examples].

To analyze statistically the situation of the National Natural Science Foundation of China (NSFC) from 2007 to 2016 in the field of acupuncture and moxibustion for supporting the national Universities colleges of traditional Chinese medicine on the General Program (GP) and the National Science Fund for Young Scholars (NSFYS). In view of five aspects, named fund, supporting units, key words, method, disorder and signal path, the differences were compared between GP and NSFYS, the following characteristics were summarized. ① The fund aid was increased from 2007 through 2013 and down-regulated from 2013 through 2016.

[Effects of Moxibustion on Ventricular Mass Index and Expression of Apoptosis Related Proteins in Myocardium of Rats with Chronic Heart Failure].

Objective: To observe the effect of moxibustion on cardiac function and the expression of B-cell lymphoma-2 (Bcl-2), Bcl-2 associated X (Bax), Fas, Fas ligand (FasL) in cardiomyocytes of chronic heart failure (CHF) rats, so as to explore its underlying mechanisms in preventing and treating CHF.

Methods: SD rats were randomly divided into normal control, model, moxibustion, Captopril and moxibustion ＋ Captopril (M＋C) groups (＝12 rats/group). The CHF model was established by intraperitoneal injection of Adriamycin (ADR, from 1 to 4 mg/kg, once every other day for 15 days).

[Effect of Moxibustion Stimulation of "Feishu" (BL 13) and "Xinshu" (BL 15) on Expression of Myocardial MyD 88 Protein and Caspase 3 mRNA in Chronic Heart Failure Rats].

Objective: To observe the effect of moxibustion stimulation of "Feishu" (BL 13) and "Xinshu" (BL 15) on pathological changes of myocardium and the expression of myocardial myeloid differentiation factor 88 (MyD 88) protein and Caspase 3 mRNA in chronic heart failure (CHF) rats, so as to explore its mechanism underlying improvement of CHF.

Methods: SD male rats were randomly divided into normal (=9), model (=8), moxibustion (=8), medication (=8) and moxibustion + medication (=8) groups. In addition, the other 6 rats (3/normal and 3/model groups) were used for measuring cardiac ventricle weight and H.