Publications by authors named "Yonglei Yang"
Diverse Transient Chiral Dynamics in Evolutionary Distinct Photosynthetic Reaction Centers.
J Chem Theory Comput
December 2024
The evolution of photosynthetic reaction centers (RCs) from anoxygenic bacteria to higher-order oxygenic cynobacteria and plants highlights a remarkable journey of structural and functional diversification as an adaptation to environmental conditions. The role of chirality in these centers is important, influencing the arrangement and function of key molecules involved in photosynthesis. Investigating the role of chirality may provide a deeper understanding of photosynthesis and the evolutionary history of life on Earth.
View Article and Find Full Text PDFLargemouth bass virus (LMBV) is an infectious pathogen that causes high mortality rates in largemouth bass, and outbreaks of this virus can significantly harm the aquaculture industry. Currently, no vaccine has been developed that can effectively prevent the transmission of LMBV. In this study, we constructed a recombinant Lactobacillus plantarum (L.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the roles of TLR3 and TRIF in the immune response to rotavirus (RV) infection, finding that their absence leads to severe damage in the small intestine of specific mice.
- Results show that dendritic cells from TLR3-/- and TRIF-/- mice struggle with antigen presentation and T cell activation, leading to reduced functionality of CD4+ and CD8+ T cells.
- The research highlights the importance of TLR3 signaling via TRIF for effective mucosal T cell responses during RV infection, providing insights that could inform the development of a new vaccine.
Avian influenza virus (AIV) subtype H9N2 has significantly threatened the poultry business in recent years by having become the predominant subtype in flocks of chickens, ducks, and pigeons. In addition, the public health aspects of H9N2 AIV pose a significant threat to humans. Early and rapid diagnosis of H9N2 AIV is therefore of great importance.
View Article and Find Full Text PDFInfluenza virus is a kind of virus that poses several hazards of animal and human health. Therefore, it is important to develop an effective vaccine to prevent influenza. To this end we successfully packaged recombinant adenovirus rAd-NP-M2e-GFP expressing multiple copies of influenza virus conserved antigens NP and M2e and packaged empty vector adenovirus rAd-GFP.
View Article and Find Full Text PDFPhosphates, whose obvious disadvantage is the relatively small birefringence, can be overcome by the introduction of post-transition metal cations containing stereochemically active lone-pair electrons. In this paper, two new compounds were successfully explored in the A-Sb-P-O system, CsSbO(PO) (CsSbPO) and (NH)SbO(HO)(PO)[PO(OH)] (NHSbPOH). Transmission spectra show that CsSbPO has a surprising transmission range with a UV cutoff edge of 213 nm.
View Article and Find Full Text PDFArticle Synopsis
- - The study focuses on piglet diarrhea caused by the porcine epidemic diarrhea virus (PEDV) in China, where it's a major health issue on farms, leading to high rates of illness and death among piglets.
- - Researchers identified three PEDV strains from piglet farms in Jilin and Shandong provinces, classifying two of them (CH/CC-1/2018 and CH/CC-2/2018) in a different genetic group compared to the traditional vaccine strain, CV777.
- - Pathogenicity tests indicated that the CH/CC-1/2018 strain was more harmful than the CH/QD/2018 strain, suggesting these new strains could help in developing more effective vaccines against PEDV
Avian influenza virus (AIV)is easy to cause diseases in birds and humans.It causes great economic losses to the poultry farms and leads to public health problems. Using vaccines is the main approach to control the prevalence of AIV.
View Article and Find Full Text PDF