Publications by authors named "Yongkang Gui"
Purpose: Postoperative cognitive dysfunction (POCD) is a common postoperative complication. Studies have reported that lymphocyte-to-monocyte ratio (LMR) was a predictor of many diseases associated with inflammation. However, further examination of the relationship between preoperative LMR and POCD is needed.
View Article and Find Full Text PDFAnesthesia and surgery activate matrix metalloproteinase 9 (MMP9), leading to blood-brain barrier (BBB) disruption and postoperative delirium (POD)-like behavior, especially in the elderly. Aged mice received intraperitoneal injections of either the MMP9 inhibitor SB-3CT, melatonin, or solvent, and underwent laparotomy under 3 % sevoflurane anesthesia(anesthesia/surgery). Behavioral tests were performed 24 h pre- and post-operatively.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the effectiveness of intra-articular injection (IAI) combined with femoral nerve block (FNB) for pain relief after total knee arthroplasty (TKA), highlighting ongoing issues with post-surgery pain management.
- Results show that patients in the IAI group experienced significantly less need for additional pain medication, lower pain scores, and a quicker return to mobility compared to those receiving periarticular injection (PAI) or FNB alone.
- The conclusion emphasizes that IAI, when used with FNB, provides better pain relief and recovery outcomes than PAI or FNB on its own.
Purpose: The application of sedation and analgesia in spinal anesthesia has many benefits, but the risk of respiratory depression (RD) caused by opioids cannot be ignored. We aimed to observe the effect of dezocine, a partial agonist of μ-receptor, on the median effective dose (ED50) of sufentanil-induced RD in patients undergoing spinal anesthesia combined with low-dose dexmedetomidine.
Patients And Methods: Sixty-two patients were randomly assigned to dezocine group (DS) and control group (MS).