Quality Evaluation of Kidney Tea Granules From Different Origins Based on TLC, HPLC Fingerprinting, and Quantitative Analysis Combined With Chemical Pattern Recognition.

Introduction: Kidney tea is an essential herbal medicine. It is widely used to treat conditions such as urinary stones, gallstones, and rheumatoid arthritis. There is currently no standardized or widely accepted research strategy for evaluating the quality of kidney tea granules (KTGs) after granulation.

Quality evaluation for Vahl granules, using TLC and HPLC fingerprint combined with chemical pattern recognition.

Vahl is a healthy food with both medicinal and culinary properties and with anti-inflammatory and anti-aging effects. There is currently no standardized or universally accepted research strategy for evaluating the quality of Vahl granules (FHGs). Therefore, the development of a comprehensive quality evaluation method is crucial for the quality control of FHGs.

New mechanistic insights of anti-obesity by sleeve gastrectomy-altered gut microbiota and lipid metabolism.

Background: The obesity epidemic has been on the rise due to changes in living standards and lifestyles. To combat this issue, sleeve gastrectomy (SG) has emerged as a prominent bariatric surgery technique, offering substantial weight reduction. Nevertheless, the mechanisms that underlie SG-related bodyweight loss are not fully understood.

Long noncoding RNA FTX is associated with prognosis of glioma patients.

Background: Long noncoding RNAs play influential roles in the progression of many types of human malignancies. The present study aimed to explore the prognostic value of long noncoding RNA FTX (FTX) on patients with glioma.

Methods: FTX expression in glioma specimens and matched adjacent non-neoplasm specimens was examined by a quantitative real-time polymerase chain reaction assay.

Effects of the combination of AsO and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1.

Context: Previous studies have demonstrated that 3'-azido-3'-deoxythymidine (AZT) and arsenic trioxide (AsO), traditional chemotherapy agents, can synergically inhibit the growth of hepatocellular carcinoma cells. However, the molecular mechanisms underlying AsO and AZT anti-hepatoma activity are unknown.

Objective: This study aimed to investigate the role of early growth response protein 1 (Egr-1) in the process of AsO combined with AZT inhibiting proliferation and inducing apoptosis of human hepatocellular carcinoma HepG2 cells, and explore the possible mechanism.