Publications by authors named "Yongjoon Choe"
Article Synopsis
- Microplastics in aquatic environments pose risks to ecosystems and human health, prompting this study on the behavior of polystyrene microplastics in various sand types.
- Through soil-column experiments, the research evaluated factors like ionic strength, breakthrough curves, and first-order attachment coefficients to understand microplastic retention.
- Results indicated that retention increased with the type of iron oxide coating on the sand, suggesting iron-rich soils could help reduce microplastic transport in aquatic systems.
Human protothecosis is mainly a cutaneous infection caused by the Prototheca species. Prototheca wickerhamii is an established pathogen of eosinophilic meningoencephalitis in dogs, but no eosinophilic pleocytosis of the cerebrospinal fluid has been reported in human cases of meningitis. Herein, we report a case of chronic protothecosis manifesting eosinophilic meningoencephalitis in an immunocompetent boy.
View Article and Find Full Text PDFAs whole genome sequencing (WGS) uncovers variants associated with rare and common diseases, an immediate challenge is to minimize false-positive findings due to sequencing and variant calling errors. False positives can be reduced by combining results from orthogonal sequencing methods, but costly. Here, we present variant filtering approaches using logistic regression (LR) and ensemble genotyping to minimize false positives without sacrificing sensitivity.
View Article and Find Full Text PDFArticle Synopsis
- Whole-genome sequencing (WGS) is revealing disease-related variants in various diseases, but accurate annotation remains a challenge for researchers due to the need for reliable computational methods.
- A new tool called gNOME has been developed to streamline the annotation and analysis of genetic variants, offering a user-friendly interface and comprehensive summaries across different levels.
- gNOME has been tested against existing datasets for cancers and has proven effective in accurately annotating variants and identifying significant genetic associations while being freely accessible to researchers.