Newton-Simpson-based predictor-corrector methods for milling chatter stability prediction.

Milling chatter, a form of self-excited vibration, can cause significant damage in machining and manufacturing processes. By selecting appropriate milling parameters, milling chatter can be effectively mitigated without sacrificing milling efficiency. Within the framework of the semi-discretization scheme, this paper introduces the Newton-Simpson-based predictor-corrector methods to compute milling stability lobe diagrams.

Research on the influence of cutter overhang length on robotic milling chatter stability.

Serial industrial robots are widely in demand in the field of large-scale component processing and manufacturing. However, the structure characteristic of serial robots makes it easy to generate chatter during milling and the overhang length of milling cutter has an important influence on the stability of robotic milling. Milling cutter overhang length refers to the length from the tip of the cutter to the protrusion of the spindle, to study the influence of milling cutter overhang length on the stability behavior of robotic milling, the modal parameters of milling cutter under different overhang length were obtained by hammer experiment, and its dynamic characteristics were analyzed.

Extensive necrotizing fasciitis of scrotum and abdominal wall: Report of two cases and a review of the literature.

The incidence rate of necrotizing fasciitis(NF) is low, but it has a high mortality rate. At present, it lacks experience in clinical treatment in municipal and county-level hospitals, insufficient awareness of disease risk, lack of experience in disease surgical intervention, and lack of a set of mature treatment norms and standards. Most patients have no time to transfer to a higher hospital for treatment.

Clinical Study on the Efficacy of Microwave Ablation (MA) in the Treatment of Stage I Renal Clear Cell Carcinoma by CT and MRI Imaging.

We have proposed an effective mechanism to corroborate the efficacy of microwave ablation (MA) in the treatment of stage I renal clear cell carcinoma in this paper. For this purpose, a total of 96 patients with stage I renal clear cell carcinoma presented in our hospital from May 2018 to January 2021 were randomly divided into CT group ( = 48) and MRI group ( = 48). Patients in both groups were treated with microwave ablation after pathological diagnosis.

increases the risk of carotid plaque formation: a clinical evidence.

Since the relation between () and atherosclerosis has been evidenced, we aimed to analyze whether there is a relationship between the patient's infection and age, gender, BMI, blood lipids, and carotid plaque formation. 810 patients from January 2016 to December 2019 were enrolled in this study, and divided the subjects into (+) group and (-) group based on the results of UBT. To analyze whether infection is related to gender, age, BMI, blood lipids, and neck vascular plaque formation.

Long Noncoding RNA LINC00707 Accelerates Tumorigenesis and Progression of Bladder Cancer via Targeting miR-145/CDCA3 Regulatory Loop.

Introduction: Growing studies reveal that long noncoding RNA is involved in oncogenesis and progression. Previous studies have demonstrated that long intergenic noncoding RNA 00707 (LINC00707) stimulated tumor progress in numerous neoplasm types; however, the function of LINC00707 in bladder cancer (BC) was not yet clear. Our researches aimed to determine whether LINC00707 was dysregulated in BC and further study its biological functions.

The effects of dialysis modality choice on cognitive functions in patients with end-stage renal failure: A protocol for systematic review and meta-analysis.

Background: There is no published meta-analysis comparing the effects of dialysis modality choice on cognitive functions in patients with end-stage renal disease . Therefore, we perform a protocol for systematic review and meta-analysis to evaluate cognitive function in peritoneal dialysis versus hemodialysis patients.

Methods: This protocol is conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocol (PRISMA-P) statement guidelines.

Current strategies with sensing technologies to eliminate stress cardiomyopathy.

Stress cardiomyopathy refers weakening of heart muscle due to the continuous stress. Generally, the severe status of stress cardiomyopathy has been revealed after damaging the muscles and measured by the physical changes in the heart system. To overcome this issue, biosensor can be used, which could eliminate the late identification stress cardiomyopathy.

Evaluation of LncRNA ANRIL Potential in Hepatic Cancer Progression.

Background/aims: LncRNAs are significant regulators in multiple cancers including hepatocellular carcinoma (HCC). Recently, lncRNA ANRIL has been reported to be elevated during multiple cancer types, exhibiting oncogenic roles. However, the exact biological mechanism of ANRIL is still poorly understood in HCC.

A Revised Hilbert⁻Huang Transform and Its Application to Fault Diagnosis in a Rotor System.

As a classical method to deal with nonlinear and nonstationary signals, the Hilbert⁻Huang transform (HHT) is widely used in various fields. In order to overcome the drawbacks of the Hilbert⁻Huang transform (such as end effects and mode mixing) during the process of empirical mode decomposition (EMD), a revised Hilbert⁻Huang transform is proposed in this article. A method called local linear extrapolation is introduced to suppress end effects, and the combination of adding a high-frequency sinusoidal signal to, and embedding a decorrelation operator in, the process of EMD is introduced to eliminate mode mixing.

[Clinical significance of cysteinyl leukotriene receptor expression in primary hepatocellular carcinoma].

Objective: To investigate expression of the cysteinyl leukotriene receptor (CysLT1R) in hepatocellular carcinoma (HCC) tissues and determine its clinical significance.

Methods: Cancerous and paraneoplastic liver tissues were collected from 30 patients with HCC and from 12 patients with liver hemangioma patients (controls). Real-time PCR and immunohistochemistry were used to evaluate the expression of CysLT1R in these tissues and assess the relationship with clinical pathological features.

[Quantifiable changes in HBeAg expression predict therapeutic efficacy of peg-interferon alfa-2a in patients with HBeAg-positive chronic hepatitis B].

Objective: To investigate whether quantifiable changes in serum levels of hepatitis B e antigen (HBeAg) in response to 24 weeks of pegylated-interferon alfa-2a (Peg-IFN-a 2a) treatment are predictive of therapeutic efficacy at 48 weeks of treatment in HBeAg-positive chronic hepatitis B (CHB) patients and to investigate the efficacy of using an individualized antiviral treatment strategy.

Methods: Ninety-six HBeAg-positive CHB patients with detectable HBeAg at week 24 of Peg-IFN-a 2a treatment were categorized according to the quantitative change in HBeAg (vs. pre-treatment baseline): group A, HBeAg decline more than 2 log; group B, HBeAg decline between 1 - 2 log; group C, HBeAg decline less than 1 log, which was then randomly divided into two sub-groups: C1 and C2.

Downregulation of GRIM-19 is associated with hyperactivation of p-STAT3 in hepatocellular carcinoma.

Accumulating evidence has implicated that constitutive activation of signal transducer and activator of transcription protein 3 (STAT3) may be a major oncogenic factor involved in hepatocellular carcinoma (HCC) development. Gene associated with retinoid-interferon-induced mortality-19 (GRIM-19) has been shown to be a tumor suppressor associated with growth control and suppression of STAT3 activity. The downregulation of GRIM-19 expression has been shown in a number of human tumor types, and it has been correlated with hyperactivation of STAT3.