Circ_0027446 promotes malignant development of glioblastoma by interacting with miR-346 to up-regulate PGK1.

Circular RNAs (circRNAs) can play essential roles in tumor development, including glioblastoma (GBM). The current study was performed to explore the function and mechanism of circ_0027446 in GBM progression. Circ_0027446, microRNA-346 (miR-346) and Phosphoglycerate kinase 1 (PGK1) levels were detected using reverse transcription-quantitative polymerase chain reaction assay.

Analysis of the Development Level of Green Economy in Different Regions Based on the GA-BP Model.

The low-carbon economy is a green development mode of modern social and economic development. In this paper, an evaluation model of the green economy development level based on GA-BP is constructed, and the related parameters and network structure of the two algorithms are designed and optimized. The test results show that the predicted value of GA-BP has a high degree of fit to the actual value, and the data fitting performance is good.

S-scheme BiVO/CQDs/β-FeOOH photocatalyst for efficient degradation of ofloxacin: Reactive oxygen species transformation mechanism insight.

Photocatalysis technology exhibited promising application for advanced treatment of wastewater. Nevertheless, the design of efficient photocatalyst and the mechanism of free radicals in pollutant degradation still remained to be further investigated. Herein, BiVO/CQDs/β-FeOOH photocatalyst was fabricated by electrostatic self-assembly method, which exhibited the excellent photocatalytic performance.

Mindfulness and Psychological Distress in Kindergarten Teachers: The Mediating Role of Emotional Intelligence.

Kindergarten teachers are often exposed to great stress. Considering that, mindfulness has been demonstrated to act as a critical role in the psychological well-being of kindergarten teachers. The present study assessed mindfulness in teaching (MT), psychological distress and emotional intelligence (EI) among 511 kindergarten teachers in mainland China and investigated the mediating role of EI to explore the association mechanism between kindergarten teachers' MT and psychological distress.

Spermidine Exhibits Protective Effects Against Traumatic Brain Injury.

Traumatic brain injury (TBI) causes permanent neurological and cognitive impairments. Effective pharmacological interventions remain elusive. Spermidine is a polyamine compound found in our body that may play a role in brain development and congenital function.

Catechin attenuates traumatic brain injury-induced blood-brain barrier damage and improves longer-term neurological outcomes in rats.

What is the central question of this study? We investigated the potential neuroprotective effects of catechin after traumatic brain injury and explored the underlying mechanisms. What is the main finding and its importance? Catechin treatment had neuroprotective effects in a rat model of traumatic brain injury, and these effects might be mediated by intervention in the self-perpetuating process of blood-brain barrier disruption and excessive inflammatory reaction. Traumatic brain injury (TBI) resulting from external force on the head usually leads to long-term deficits in motor and cognitive functions.