Flora colonization and oral care in high-risk newborns.

Purpose: A randomized intervention study was conducted to explore the impact of oral care with sterile normal saline to oral flora colonization of high-risk newborns at the third day after birth.

Design And Methods: Ninety-two newborns were allocated to either intervention or control group. After obtaining oral secretion for prepoint data, the intervention group received oral care with sterile normal saline only.

Two methods of cord care in high-risk newborns: their effects on hydration, temperature, pH, and floras of the cord area.

This randomized clinical study explored the effects of two cord care methods on hydration, temperature, pH, and floras at the cord area in high-risk newborns. One group used the water method; and the other group used the alcohol method. Seventy-two newborns, including premature newborns, in the neonatal intensive care unit (NICU) of a university-affiliated hospital in South Korea were enrolled from August 2011 to May 2012.

Growth patterns and their implications for preterm infants in a culture of rapid modernization.

This prospective longitudinal study explored the growth patterns of preterm infants and the implications of rearing them in an advancing culture. The study measured the weight, length, and head circumference of 343 Korean preterm infants over 12 months corrected age. Data were analyzed using a generalized estimation equation for growth patterns of preterm infants by the degree of prematurity (mild, moderate, or severe).

Congenital acute myeloid leukemia with t(8;16) and t(17;19) double translocation: case presentation and literature review.

Congenital leukemia is uncommon and excluding transient myeloproliferation associated with Down syndrome, makes up approximately 1% of childhood leukemias. A newborn boy was born with multiple subcutaneous nodules and large purpuric papules. Skin biopsy revealed proliferation of atypical hematologic cells in the dermis.

Topiramate monotherapy in infantile spasm.

Infantile spasm is an age-related refractory epilepsy. Topiramate is a new anticonvulsant with multiple mechanisms of action, and it may be effective for treating pediatric epilepsies. To evaluate the efficacy and tolerability of first-line topiramate treatment for infantile spasm, 20 patients received topiramate monotherapy during this study.

Measurement of pain-like response to various NICU stimulants for high-risk infants.

Background: Infants during neonatal intensive care are invariably exposed to various procedural and environmental stimuli in which the pain-like responses may vary depending on the nature of the stimuli and the infants' condition.

Aim: To examine firstly the pain-like responses to frequent stimulants in the neonatal intensive care unit (NICU) using CRIES, FLACC and PIPP, and secondly the clinical feasibility and validity of using these pain measurements for high-risk infants.

Study Design And Subjects: In a correlational study of 110 premature infants receiving neonatal intensive care, the pain-like responses to 274 observations of 8 types of frequently applied stimulant, classified into three categories according to the degree of invasiveness, were observed using CRIES, FLACC and PIPP.

[Assessment of neonatal hyperbilirubinemia using a transcutaneous bilirubinometry].

Purpose: The purpose of the study is to investigate the relationship between total serum bilirubin(TSB) and transcutaneous bilirubinometry(TcB) in neonates with jaundice.

Method: TcB from various sites(forehead, sternum, abdomen, buttock, hand, dorsalis-pedia) was measured using a JM-102 in a total of 102 neonate, 42 female and 60 male, with the mean 37.5 gestational week and the mean 2,903 gram of birth weight, as well as TSB from capillary punctures.

The effects of the shallow and the deep endotracheal suctioning on oxygen saturation and heart rate in high-risk infants.

An experimental study involving repeated-measures within subjects was conducted to examine the effects of shallow and deep endotracheal suctioning (ETS) on the SpO(2) and HR in 27 ventilated high-risks infants. The order in which subjects received the ETS protocol was randomly assigned. The results showed no significant changes in both the SpO(2) and HR responses before, during and after ETS between the two ETS protocols.