Publications by authors named "Yonghong S"

Telocytes (TCs), a novel type of interstitial cells, are characterized by their smaller cellular body and extremely long, thin processes which are called telopodes (Tps). They have been described in multiple organs from diverse animals. Currently, the existence of TCs in rat pars distalis (PD) has remained unexplored.

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Article Synopsis
  • Forests impact climate through biochemical and biophysical processes, with biophysical effects being particularly significant in arid regions, which have been less studied compared to other zones.
  • This study used measurements and modeling to assess how arid forests affect surface temperatures, finding that despite absorbing more radiation, these forests generally cool the temperature annually with notable seasonal variations.
  • Evapotranspiration from the forests was the main factor in cooling, while surface albedo and incoming longwave radiation contributed to warming, indicating that arid forests play a crucial role in regulating climate trends.
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In order to clarify fine structures of the hypothetical meridian conduits of Chinese traditional medicine (CTM) in the skin, the present study used light and transmission electron microscopy to examine fasciae in different vertebrate species. Collagen fiber bundles and layers were arranged in a crisscross pattern, which developed into a special tissue micro-channel (TMC) network, in a manner that was analogs to the proposed skin meridian conduits. It was further revealed that tissue fluid in lateral TMC branches drained into wide longitudinal channels, which were distinctly different from lymphatic capillary.

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Telocytes (TCs) are very long, non-neuronal, somatic cells whose function is widely believed to be involved in providing connections between different cells within the body. The cellular characteristics of TCs in various organs have been studied by immunohistochemistry, double immunofluorescence and electron microscopy in different vertebrate species, and here we investigate the proposed properties of these cells in the context of the "meridian" in Chinese Traditional Medicine (CTM). The results show that TCs and their long extensions, telopodes (Tps) develop a complicated network by homo- and heterocellular junctions in the connective tissue throughout the body, which can connect the skin with distant organs.

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The need for environmental protection challenges societies to deal with difficult problems because strategies designed by scientists to protect the environment often create negative effects on impoverished local residents. We investigated the effects of China's national and regional policies related to environmental protection and rehabilitation projects in inland river basins, by studying the effect of projects in the Heihe and Shiyang river basins, in northwest China. Interviews and surveys were conducted at 30 sites in the lower reaches of these two arid basins, an area that has experienced severe ecological degradation.

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  • - The study investigates how SREBP-1, a transcription factor, regulates fatty acid and triglyceride synthesis and its connection to lipid accumulation in diabetic kidneys, using type 1 diabetic rat models and human kidney cells.
  • - Results showed that SREBP-1 and triglyceride levels increased in diabetic rat kidney, leading to higher TGF-beta1 and extracellular matrix accumulation, while human kidney cells indicated that increased SREBP-1 led to more lipid droplet formation.
  • - High glucose levels positively influenced SREBP-1 expression in renal cells, and the study successfully developed plasmid vectors to inhibit SREBP-1 expression, demonstrating significant reductions in both mRNA and protein levels of SREBP-1.
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