Publications by authors named "Yonghao Bi"
Article Synopsis
- - Osteoporosis is a serious condition causing weakened bones and increased fracture risk, particularly in older individuals, highlighting the need for better treatment options with fewer side effects.
- - Trifolirhizin, a natural compound from Sophora flavescens, was studied for its effects on osteoclast formation and function, showing potential in reducing bone resorption and protecting against bone loss in mice.
- - The research found that trifolirhizin inhibits key signaling pathways related to bone loss, suggesting it could be a promising therapeutic agent for osteoporosis and related diseases.
Background: Several studies have reported the association between osteoporosis and major depressive disorder (MDD) as well as the use of antidepressants. However, it remains to be elucidated whether these associations are related to exposure to antidepressants, a consequence of a disease process, or a combination of both.
Methods: This study investigates the independent effect of the antidepressant duloxetine hydrochloride (DH) on ovariectomy-induced bone loss in mice.
Brevilin A inhibits RANKL-induced osteoclast differentiation and bone resorption.
In Vitro Cell Dev Biol Anim
June 2023
Brevilin A (BA) is the primary component of Centipeda minima, which is widely used in Chinese traditional medicine. The anti-inflammatory and anti-tumor properties of BA have been established; however, its function in bone metabolism is not well understood. This study revealed that concentrations of BA below 1.
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