Endoscopic ultrasound-based application system for predicting endoscopic resection-related outcomes and diagnosing subepithelial lesions: Multicenter prospective study.

Objectives: Subepithelial lesions (SELs) are associated with various endoscopic resection (ER) outcomes and diagnostic challenges. We aimed to establish a tool for predicting ER-related outcomes and diagnosing SELs and to investigate the predictive value of endoscopic ultrasound (EUS).

Methods: Phase 1 (system development) was performed in a retrospective cohort (n = 837) who underwent EUS before ER for SELs at eight hospitals.

Optimal method for determining the intraclass correlation coefficients of urinary biomarkers such as dialkylphosphates from imputed data.

Urinary biomarkers are commonly used in epidemiological studies as surrogates or indicators of exposure to chemical substances. Evaluating the reliability of a biomarker is highly important because use of an unreliable marker may lead to misclassification and attenuation bias, resulting in flawed interpretations and conclusions. Although intraclass correlation coefficient (ICC) is regarded as a typical index of test reliability, methods for determining the ICCs of urinary biomarkers have not been standardised, and different methods have been used.

Profiling Airborne Microbiota in Mechanically Ventilated Buildings Across Seasons in Hong Kong Reveals Higher Metabolic Activity in Low-Abundance Bacteria.

Metabolically active bacteria within built environments are poorly understood. This study aims to investigate the active airborne bacterial microbiota and compare the total and active microbiota in eight mechanically ventilated buildings over four consecutive seasons using the 16S rRNA gene (rDNA) and the 16S rRNA (rRNA), respectively. The relative abundances of the taxa of presumptive occupants and environmental origins were significantly different between the active and total microbiota.

Diurnal and weekly patterns of primary pollutants in Beijing under COVID-19 restrictions.

Restrictions on movement in Beijing to limit the COVID-19 epidemic tended to reduce the emissions of primary pollutants. However, changes in pollutant concentrations are also affected by chemical transformation and meteorology. Decreases in concentrations were also not as obvious in Beijing when compared with Hubei Province, where lockdown was especially strict.

Airborne Bacteria in Outdoor Air and Air of Mechanically Ventilated Buildings at City Scale in Hong Kong across Seasons.

Studies of the indoor airborne microbiome have mostly been confined to a single location and time point. Here, we characterized, over the course of a year, the geographic variation, building-function dependence, and dispersal characteristics of indoor and outdoor airborne microbiomes (bacterial members only) of eight mechanically ventilated commercial buildings. Based on the Sloan neutral model, airborne microbiomes were randomly dispersed in the respective indoor and outdoor environments and between the two environments during each season.

Regulatory effects on particulate pollution in the early hours of Chinese New Year, 2015.

Human activities are a key driver of air pollution, so it is hardly surprising that celebrations affect air quality. The use of fireworks contributes to high particulate concentrations in many parts of the world, with the Chinese Lunar New Year (spring festival) particularly noticeable, as firecrackers are traditionally used to drive off evil spirits. Fireworks lead to short-term peaks in the concentration of PM10, PM2.