Publications by authors named "Yongfei Jiang"
Article Synopsis
- The study investigates S100β as a biomarker for astroglial damage and its effect on prognosis in patients with acute ischemic stroke after intravenous thrombolysis (IVT).
- Researchers analyzed data from 1072 patients, measuring S100β levels 24 hours post-IVT, and found that higher levels were linked to worse outcomes, larger infarct volumes, and higher NIHSS scores.
- Notably, S100β levels had a stronger correlation with outcomes in patients with dominant hemisphere strokes compared to those with non-dominant strokes.
Whether the dynamic development of peripheral inflammation aggravates brain injury and leads to poor outcome in stroke patients receiving intravenous thrombolysis (IVT), remains unclear and warrants further study. In this study, total of 1034 patients with acute ischemic stroke who underwent IVT were enrolled. Serum leukocyte variation (whether increase from baseline to 24 h after IVT), National Institutes of Health Stroke Scale (NIHSS), infarct volume, early neurologic deterioration (END), the unfavorable outcome at 3-month (modified Rankin Scale [mRS] score ≥3) and mortality were recorded.
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