Publications by authors named "Yongchi Zhan"
Article Synopsis
- Brodifacoum is a highly effective rodent poison that can cause serious bleeding issues (coagulopathy), but its effects during pregnancy are not well documented.
- A case study reported a pregnant woman experiencing severe bleeding due to brodifacoum poisoning, leading to serious complications and the loss of the fetus.
- Effective management of brodifacoum poisoning is essential, with timely recognition and treatment (like vitamin K1) needed to improve outcomes for pregnant patients.
Article Synopsis
- Placenta previa accreta (PPA) can lead to severe blood loss during cesarean hysterectomy, sometimes requiring the procedure to prevent life-threatening hemorrhage.
- A study of 199 women undergoing cesarean sections found that factors like emergency surgery, cervical invasion of the placenta, and bladder injury increased the risk of excessive blood loss.
- Conversely, techniques like balloon occlusion of the iliac arteries and aortic balloon occlusion appeared to reduce the risk of significant blood loss during surgery.
Article Synopsis
- Intrahepatic cholestasis of pregnancy (ICP) can cause problems for babies, but how it affects their growth is still unclear.
- In a study of 97 moms with ICP and 152 healthy moms, researchers looked at how the babies grew over three years and checked the moms' liver health.
- They found that babies of moms with ICP were shorter and weighed less in their first year, and had higher risk of stunted growth compared to babies of healthy moms.
Objective: Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse perinatal outcomes, resulting in a higher risk of perinatal morbidity and mortality.
Methods: The authors conducted a retrospective study of 2385 singletons with ICP who underwent risk-stratified management strategies. To explore the risks of perinatal outcomes of ICP, subgroup analyses were performed using different total bile acid (TBA) levels.
Placenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of placental separation in the third stage of labor. A protuberance with gross subserous blood vessels in the left fundus of the uterus was detected and was misdiagnosed as placental accreta.
View Article and Find Full Text PDFIntrahepatic cholestasis of pregnancy and fetal cardiac dysfunction: a systematic review and meta-analysis.
Am J Obstet Gynecol MFM
August 2023
Objective: Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes. Fetal cardiac dysfunction may be 1 part of the pathophysiology of pregnancies complicated by intrahepatic cholestasis of pregnancy. This systematic review and meta-analysis aimed to evaluate the association between intrahepatic cholestasis of pregnancy and fetal cardiac dysfunction.
View Article and Find Full Text PDFObjective: Listeriosis is a rare but severe foodborne disease that is contracted by the consumption of food contaminated with , and perinatal listeriosis can cause major adverse pregnancy outcomes. In the current study, we sought to retrospectively analyze 10 years of perinatal outcomes due to listeriosis in western China.
Methods: Based on the isolation of (), we retrospectively reviewed the pregnancy-associated cases of listeriosis from June 2010 to February 2022 at our hospital.
Unique microRNA expression profiles in plasmic exosomes from intrahepatic cholestasis of pregnancy.
BMC Pregnancy Childbirth
March 2023
Background: Intrahepatic cholestasis of pregnancy (ICP) is strongly associated with an increased risk of adverse perinatal outcomes. Total bile acid (TBA) levels in the late second or third trimester are a major factor in the diagnosis. Here, we sought to establish the miRNA expression profile of plasm exosomes of ICP and identify possible biomarkers for the diagnosis of ICP.
View Article and Find Full Text PDFBackground: Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse perinatal outcomes leading to high perinatal morbidity and mortality. However, few studies have examined twin pregnancies complicated by ICP. To assess the perinatal outcomes of twin pregnancies with ICP, a retrospective cohort study was conducted.
View Article and Find Full Text PDFIntrahepatic cholestasis of pregnancy and maternal dyslipidemia: a systematic review and meta-analysis.
Acta Obstet Gynecol Scand
July 2022
Introduction: The association between intrahepatic cholestasis of pregnancy (ICP) and maternal lipid metabolism remains unknown. This systematic review and meta-analysis aimed to evaluate the association between ICP and maternal lipid metabolism.
Material And Methods: We systematically searched Medline, Embase and the Cochrane Library (up to December 11, 2021) to identify relevant studies that investigated ICP and maternal plasma lipid concentrations.