Publications by authors named "Yongbin Pei"

Article Synopsis
  • This study evaluates the impact of precision health management paired with DXA therapy on bone health in elderly patients with osteoporosis, comparing it to standard treatment.
  • A total of 236 patients were split into two groups: one received the combined treatment, and the other received standard care, with various health indicators measured over two years.
  • Results indicated that the precision health approach improved bone mineral density, reduced pain levels, and enhanced knowledge and self-management confidence in the observation group compared to the control group.
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  • This study investigates how serum levels of vitamin D3 (25(OH)D3) relate to carotid artery thickness (CIMT) and plaque presence in smokers aged 52 to 73.
  • Of 469 patients examined, those with low vitamin D3 levels (<30 ng/mL) had thicker artery walls and more plaques compared to those with normal levels (30-50 ng/mL).
  • The findings indicate that lower vitamin D3 levels are associated with worse artery health and higher cholesterol levels in smokers, suggesting vitamin D3 could play a role in carotid artery disease.
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  • The study investigates the effectiveness of fecal microbiota transplantation (FMT) in treating mild to moderate COVID-19 symptoms in a cohort of 40 patients.
  • Results indicate that FMT significantly improved digestive symptoms like diarrhea and neuropsychiatric issues such as depression, with notable reductions in symptom severity compared to a placebo group.
  • Additionally, FMT was associated with a decrease in a biomarker related to long COVID-19, suggesting it could be a promising treatment strategy for managing lingering symptoms in COVID-19 patients.
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Purpose: This study was aimed to study the hypothesis that forkhead box O1 (FOXO1) gene rs17446614 and rs17592236 single nucleotide polymorphisms (SNPs) influenced the development of diabetic nephropathy (DN).

Methods: This study included 138 DN patients and 149 healthy controls. Controls were matched with the patients in age and gender.

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Objective: To detect plasma miR-106a level in patients with colorectal cancer (CRC) and analyze its correlation to the clinicopathological features and disease diagnosis.

Methods: miRNA expression profiling was performed using miRNA microarray chip for 3 colorectal adenocarcinoma samples and matched normal tissues. Plasma samples was collected from 50 colorectal cancer patients for quantitative analysis of miR-106a using real-time RT-PCR using 47 plasma samples from healthy volunteer as the control.

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Background: Meningioma-associated protein (MAC30), first described to be overexpressed in meningiomas, exhibits altered expression in certain human tumors. The aim of our study was to investigate the expression of MAC30 mRNA and its correlation with clinicopathological variables in human colorectal cancer (CRC).

Methods: MAC30 mRNA expression was first examined in 55 CRCs, along with the samples from the matched distant normal and adjacent noncancerous tissue by RT-PCR, further verified in 18 CRCs by quantitative RT-PCR.

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