Effects of conditions for preparing nanoparticles composed of aminoethylcarbamoyl-beta-cyclodextrin and ethylene glycol diglycidyl ether on trap efficiency of a guest molecule.

Nanoparticles comprising copolymers of aminoethylcarbamoyl-beta-cyclodextrin (AEC-beta-CD) and ethylene glycol diglycidyl ether (EGDGE) are prepared by an interfacial polyaddition reaction in a miniemulsion system. Polymers are formed in a W/O emulsion containing 0.25-10.

Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system.

Nanostuctured lipid carriers (NLC) based on mixture of solid lipids with spatially incompatible liquid lipids are a new type of lipid nanoparticles, which offer the advantage of improved drug loading capacity and release properties. In present study, stearic acid (SA) nanostuctured lipid carriers with various oleic acid (OA) content were successfully prepared by solvent diffusion method in an aqueous system. The size and surface morphology of nanoparticles were significantly influenced by OA content.

Trap and release of oligonucleotide using pH-responsive amphoteric particle prepared by interfacial polymerization in W/O miniemulsion system.

Novel amphoteric particles are prepared by an interfacial polyaddition reaction of ethylene glycol diglycidyl ether (EGDGE) and L-lysine in a water-in-oil (W/O) miniemulsion system. The zeta-potential of the copolymer particle as a function of pH indicates a sigmoid curve with an isoelectric point at pH 8.7 due to the existence of secondary amino and carboxyl groups in the copolymer chain.

Motor protein nano-biomachine powered by self-supplying ATP.

A new nano-biomachine has been created from microtubules (MTs) and hetero-bifunctional polymer particles bearing pyruvate kinase, which is propelled on glass surfaces coated with kinesin by use of self-supplying ATP.

Biotinylated and enzyme-immobilized carrier prepared by hetero-bifunctional latex beads.

Biotinylated and pyruvate kinase immobilized nano-bio element have been prepared using hetero-bifunctional latex beads, where the enzyme activity is roughly half of the free enzyme.