Zhonghua Yu Fang Yi Xue Za Zhi
September 2010
Objective: To explore the relationship between the -344T/C polymorphism of aldosterone synthase (CYP11B2) gene and essential hypertension in Chinese Mongolian population.
Methods: By cluster-sampling method, a total of 1575 Mongolian people in Tongliao city of Inner Mongolia were included in this study. And 417 subjects were normotension, 596 subjects were prehypertension and 562 subjects were essential hypertension.
The present study aimed to explore gene-gene and gene-environment interactions among three candidate genes and several environmental risk factors, and their impacts on hypertension in Chinese Mongolian population. A cross-sectional study was conducted in 2003-2004 among 1,575 Mongolian people in Tongliao City of Inner Mongolia, China. Epidemiologic and clinical data and blood samples were obtained from subjects.
View Article and Find Full Text PDFObjective: To explore the interaction between C (-344) T polymorphism of CYP11B2 and drinking index (DI) as well as their impact on the risk of hypertension in Chinese Mongolian population.
Methods: A total of 1575 Mongolian people aged 20 and older including 562 hypertensive and 1013 normal-tensive from agricultural and pastoral areas in Tongliao city of Inner Mongolia, were included in this study. A cross-sectional survey was conducted to collect data by personal interview with local residents, using a standard questionnaire.
Zhonghua Liu Xing Bing Xue Za Zhi
October 2006
Objective: To investigate the association of specific functional gene ACE (I/D) variants of the renin-angiotensin system with essential hypertension (EH) and interaction between ACE (I/D) gene and risk factors for EH in a genetically homogenous Mongolia rural population of China.
Methods: Individuals (n=1099) were recruited from general population of Kezuohouqi Banner in Inner Mongolian Autonomous Region.
Results: The association was found between ACE genotype DD plus ID and EH, with an interaction between ACE genotype DD plus ID and cigarette smoking in an additive model.