Oral edaravone ameliorates behavioral deficits and pathologies in a valproic acid-induced rat model of autism spectrum disorder.

Autism spectrum disorder (ASD) is neurodevelopmental disorder with a high incidence rate, characterized by social deficits and repetitive behaviors. There is currently no effective management available to treat the core symptoms of ASD; however, oxidative stress has been implicated in its pathogenesis. Edaravone (EDA), a free-radical scavenger, is used to treat amyotrophic lateral sclerosis (ALS) and acute ischemic stroke (AIS).

Remediation of diesel contaminated soil by using activated persulfate with FeO magnetic nanoparticles: effect and mechanisms.

In this study, FeO magnetic nanoparticles (FeO MNPs) were assessed for their ability to enhance the activity of persulfate (PS). Various controlling factors including PS dosages, initial pH, water-soil ratio, ratio of Fe, and FeO MNPs to PS were considered in both the Fe/PS system and the FeO MNPs/PS system. Results showed that the FeO MNP-activated PS system exhibited high processing efficiency owing to the gradual release of Fe.

Arbuscular Mycorrhizal Fungus Alleviates Charged Nanoplastic Stress in Host Plants via Enhanced Defense-Related Gene Expressions and Hyphal Capture.

Contamination of small-sized plastics is recognized as a factor of global change. Nanoplastics (NPs) can readily enter organisms and pose significant ecological risks. Arbuscular mycorrhizal (AM) fungi are the most ubiquitous and impactful plant symbiotic fungi, regulating essential ecological functions.

Changes in coagulation markers in children with Mycoplasma pneumoniae pneumonia and their predictive value for Mycoplasma severity.

Background: This study investigates the correlation between coagulation levels and the severity of Mycoplasma pneumoniae pneumonia (MPP) in children. In addition, the study analyses the predictive value of coagulation abnormalities in MPP combined with necrotising pneumonia (NP).

Methods: A total of 170 children with MPP who underwent treatment between June 2021 and February 2022 were selected for this study.

[Transport and Model Calculation of Microplastics Under the Influence of Ionic Type, Strength, and Iron Oxide].

Microplastics (MPs) in soil have attracted extensive attention as an emerging pollutant, and the transport of MPs is affected by their own physical and chemical properties, the chemical composition of soil solutions, and soil minerals. However, in the presence of oxides, the underlying mechanism for the transport of MPs in different ionic types and ionic strengths is still not fully understood. In this study, the effects of ionic type, ionic strength, and iron oxide on the transport of polystyrene microplastics (PSMPs) with different functional groups were investigated through stability experiments and transport experiments.

[Characteristics of Antibiotic Contamination of Soil in China in Past Fifteen Years and the Bioremediation Technology: A Review].

In recent years, the contamination of antibiotics and their resistance genes (ARGs) has attracted the extensive attention of researchers at home and abroad. Soil is an important sink for the migration and transformation of antibiotics and ARGs, which pose a threat to soil organisms and human health. According to the relevant investigations in the past 15 years, the soil has been polluted by antibiotics to varying degrees in China.

[Effects of pH, Calcium, and Phosphate on the Solubility of Arsenic in Paddy Soil Based on Surface Complexation Modeling].

This study aimed to obtain a better understanding on the environmental behavior of As in paddy soil and to reveal the influence mechanisms of different environmental factors on the availability of As in the soil solution. The effects of pH, calcium, and phosphate on the solubility and speciation distribution of As in the paddy soil collected from Zhuzhou of Hunan province were studied by combining the adsorption experiments with the NOM-CD model. The results showed that the minimum concentration of soluble As in the soil was at approximately a pH of 6.

Evaluation of immunogenicity and protective efficacy of a novel Senecavirus A strain-based inactivated vaccine in mice.

Senecavirus A (SVA) is an emerging picornavirus associated with porcine idiopathic vesicular disease (PIVD), which is clinically indistinguishable from foot-and-mouth disease and other vesicular diseases in pigs. In recent years, the wide spread of SVA has caused huge economic losses to the world's pig industry. However, there are no vaccines currently available to prevent and control the infection of SVA due to the extensive diversity of SVA isolates and high cost of the pig model for vaccine evaluation.

Development and application of SYBR Green Ⅰ real-time quantitative reverse transcription PCR assay for detection of swine Getah virus.

Getah virus (GETV), a mosquito-borne virus belonging to the Alphavirus genus of family Togaviridae, has become increasingly problematic, which poses a huge threat to the safety of animals and public health. In order to detect GETV quickly and accurately, we have developed a SYBR Green I real-time quantitative reverse transcription PCR (RT-qPCR) assay for GETV with the detection limit of 66 copies/μL, excellent correlation coefficient (R) of 0.9975, and amplification efficiency (E) of 98.

Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province, China.

The aim of this study was to evaluate the safety of an antiviral regimen of protease inhibitors combined with Arbidol (umifenovir) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia patients. The genomic sequence of SARS-CoV-2 is highly homologous to that of SARS-CoV (Zhou et al., 2020).

Utilizing dexamethasone intravitreal implant to control postoperative inflammation in refractory uveitis undergoing cataract surgery.

Aim: To report the effectiveness of intravitreal implantation of dexamethasone implant (Ozurdex) after phacoemulsification and intraocular lens implantation in refractory uveitis patients.

Methods: This single-center retrospective study conducted for refractory pan-uveitis patients who underwent cataract surgery combined with intravitreal Ozurdex implantation. The main outcome measurements were best-corrected visual acuity (BCVA), central retinal thickness (CRT), grade of anterior chamber cell (AAC), intraocular pressure (IOP), and systemic/ocular adverse events.

Removal of cadmium from wastewater by magnetic zeolite synthesized from natural, low-grade molybdenum.

Zeolite has a high adsorption capacity for heavy metals, but it is difficult to separate from the medium because of its small particle size. In this study, magnetic zeolite was synthesized from natural, low-grade molybdenum ore by adding nano ferroferric oxide (saturation magnetization 83.43 emu/g) directly in the hydrothermal synthesis process, which was used to adsorb cadmium from wastewater.

Rhizosphere iron and manganese-oxidizing bacteria stimulate root iron plaque formation and regulate Cd uptake of rice plants (Oryza sativa L.).

Iron plaque is the amorphous and/or crystalline layer of Fe and Mn (hydr)oxides formed on the root surface of wetland plants. It could adsorb and co-precipitate metal(loid)s at the rhizosphere, thus modulating the uptake and accumulation of metal elements in plants. In this study, the Fe(II)/Mn(II)-oxidizing bacteria Burkholderia sp.

The role of GtxA during Gallibacterium anatis infection of primary chicken oviduct epithelial cells.

Gallibacterium anatis (G. anatis), one of the major pathogens causing reproductive tract disorders in laying hens, leads to a reduction in egg production and increased mortality, caused by either single or mixed infections with other pathogens. As a specific virulence factor of G.

Current Status and Prospects of Spontaneous Peritonitis in Patients with Cirrhosis.

Spontaneous bacterial peritonitis (SBP) is a common cirrhotic ascites complication which exacerbates the patient's condition. SBP is caused by gram-negative bacilli and, to a lesser extent, gram-positive cocci. Hospital-acquired infections show higher levels of drug-resistant bacteria.

[Stability of Ferrihydrite and Goethite Nanoparticles Under Different Environmental Conditions].

Agglomeration and dispersion of nanoparticles control many important environmental processes. In this study, the particle size and zeta potential of ferrihydrite nanoparticles (FHNPs) and goethite nanoparticles (GTNPs) under different pH, ion, and organic matter conditions were measured. These data were used to calculate the Derjaguin-Landau-Verwey-Overbeek (DLVO) interaction energy between nanoparticles to further investigate the stability of two nanoparticles.

Manure fertilization increase antibiotic resistance in soils from typical greenhouse vegetable production bases, China.

A large quantity of manure is applied in greenhouse vegetable production (GVP) soils, while manure fertilization often leads to the proliferation of antibiotic resistance genes (ARGs) in soils. However, comprehensive study on the effects of different types of manure on ARGs in GVP soils remains unknown, and the baseline level of ARGs in GVP soil is poorly quantified. This study conducted a comprehensive survey of ARGs in GVP soils using high-throughput quantitative PCR.

Protection of chickens against hepatitis-hydropericardium syndrome and Newcastle disease with a recombinant Newcastle disease virus vaccine expressing the fowl adenovirus serotype 4 fiber-2 protein.

Newcastle disease (ND) is one of the most important and devastating avian diseases with considerable threat to the global poultry industry. Hepatitis-hydropericardium syndrome (HHS), caused by virulent fowl adenovirus serotype 4 (FAdV-4), is another highly infectious disease in chickens with severe economic impact. The effective way to combat ND and HHS is by vaccinating the poultry.

Remediation of petroleum hydrocarbon contaminated soil by using activated persulfate with ultrasound and ultrasound/Fe.

This study investigates the degradation of petroleum hydrocarbon in contaminated soil using activated persulfate (PS) with ultrasound (US) and US/Fe. Various controlling factors including different PS dosage, ultrasonic power, pH, soil water ratio and soil particle size were considered. It was found that petroleum hydrocarbon degradation efficiency achieved up to 56.

An advanced sol-gel strategy for enhancing interfacial reactivity of iron oxide nanoparticles on rosin biochar substrate to remove Cr(VI).

The application of iron oxide nanoparticles (IONs) is often limited by agglomeration and low loading. Here, we presented a facile phase change material (PCM) -based sol-gel strategy for the fabrication of α-FeO nanoparticles. Rosin was used as the PCM in the sol-gel process and the carbon-based substrate of α-FeO nanoparticles in the thermal process.

Exchange-biased hybrid γ-FeO/NiO core-shell nanostructures: three-step synthesis, microstructure, and magnetic properties.

A two-step solvothermal method combining a calcination process was conducted to synthesize γ-Fe2O3/NiO core-shell nanostructures with controlled microstructure. The formation mechanism of this binary system has been discussed, and the influence of microstructures on magnetic properties has been analyzed in detail. Microstructural characterizations reveal that the NiO shells consisted of many irregular nanosheets with disordered orientations and monocrystalline structures, packed on the surface of the γ-Fe2O3 microspheres.

Risk factors for Clostridium difficile infection in cirrhotic patients.

Background: Cirrhotic patients are susceptible to Clostridium difficile infection (CDI), however, the high risk factors are not clear. The present study aimed to identify the risk factors in cirrhotic patients with CDI.

Methods: A total of 526 cirrhotic patients admitted to our hospital between May 2015 and October 2015 were included in this study.

Removal of persistent DDT residues from soils by earthworms: A mechanistic study.

Earthworms have been reported to enhance DDT (1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane) removal from soils, but the mechanism underlying is still poorly understood. This study therefore worked on the links between DDT transformation in drilosphere and non-drilosphere matrices and the properties of these matrices in sterile and non-sterile soil columns with and without earthworms to reveal related mechanisms. The results show that earthworms shortened the half-time of DDT in soils from over 14 weeks to about 8 weeks; DDT residues were lower (p < 0.