[Flavorand taste change rules of Sophora Flavescentis Radix processed using ancient classical method:an exploration based on intelligent sensory analysis].

This study was designed to investigate the flavor and taste change rules of Sophora Flavescentis Radix processed using the ancient classical method documented in Master Lei's Discourse on Medicinal Processing(Lei Gong Pao Zhi Lun). The Sophora Flavescentis Radix pieces and the corresponding test samples in each processing stage were first prepared based on the processing method for Sophora Flavescentis Radix recorded in Master Lei's Discourse on Medicinal Processing(Lei Gong Pao Zhi Lun). Then the flavors and tastes of Sophora Flavescentis Radix test samples undergoing the soaking in rice-washed water, washing with clean water, and steaming for different time were compared with the electronic nose and tongue.

[Similar change laws of content of nine components in four processing methods of Polygoni Multiflori Radix Praeparata].

To standardize the processing technology of Polygoni Multiflori Radix Praeparata and stabilize its quality, the similar change laws of Polygoni Multiflori Radix Praeparata with different processing methods and time were analyzed. The processing time of Polygoni Multiflori Radix Praeparata was studied at 24, 32, 40, 48 h, and 4 different processing methods were studied, namely stewed with black bean sauce, steamed, steamed with black bean sauce, and steamed with black bean sauce and rice wine. The content of stilbene glycosides and anthraquinones were determined by HPLC-DAD method.

[Transformation of production mode and innovation of production technology of decoction pieces of Chinese crude drugs-feasibility study on intelligent production of decoction pieces of Chinese crude drugs].

With the publishment of the application guideline for the key project of "Research on Modernization of Traditional Chinese Medicine" by the Ministry of Science and Technology in 2018, the problem of "intelligentization" in the production of decoction pieces of Chinese crude drugs has attracted more and more attention from the industry. Some suggestions on the intelligentization of the production of decoction pieces of Chinese crude drugs in the course of transformation of production mode and innovation of production technology of decoction pieces of Chinese crude drugs" were proposed in this paper, which in order to help the implementation of the project and the development of decoction pieces industry.

[Development and innovation of traditional Chinese medicine processing discipline and Chinese herbal pieces industry].

To elucidate the key issues in the development and innovation of traditional Chinese medicine processing discipline and Chinese herbal pieces industry Chinese herbal pieces industry. According to the author's accumulated experience over years and demand of the development of the Chinese herbal pieces industry, the key issues in the development and innovation on the Chinese herbal pieces industry were summarized. According to the author, the traditional Chinese medicine processing discipline shall focus on a application basis research.

Global metabolite profiling and diagnostic ion filtering strategy by LC-QTOF MS for rapid identification of raw and processed pieces of Rheum palmatum L.

Due to its variety of functions, rhubarb has been used for thousands of years in many countries. It is commonly used after processing. Processing usually affect the chemical profile and the contents of active compounds in herbals, leading to changes of their bioactivities.

[To accelerate pace of studying standard pieces of Chinese medicine as standard material].

Objective: To elucidate the necessary and research of accelerating basic research of Chinese standard pieces as standard materials.

Method: According to over 10 years accumulated experience and be keenly aware of the author, the evaluation method of standardized processing technology and Chinese pieces quality, aimed at consummated the standard material of the quality evaluation of Chinese herbal pieces at the current situation, and inaccordance with the need of improving quality standard system of Chinese herbal pieces, illustrate the necessity of accelerating basic research of Chinese standard pieces as standard materials; from the technical specification for collecting and processing of raw materials, and the technical specification, homogenized sample, packaging, storage and etc., for processing of candidate standard pieces, determine the methods and steps of technical specifications for standard pieces as the standard substance, determine the methods and steps of technical specifications for standard pieces as the standard substance.

[Content comparison of main chemical compositions in Gardenia jasminoids roasted with ginger juice].

Objective: To compare the contents of the main chemical compositions in Gardenia jasminoids before and after being roasted with ginger juice.

Method: Four diterpenoid pigments constituents (C-1, C-2, C-3, crocetin) were determined simultaneously by UPLC on an Agilent Poroshell 120 EC-C18 column at 35 degrees C with the methanol-0.5% formic acid anhydrous in gradient elution as the mobile phrase.

[Chemical constituents from roots of Peucedanum praeruptorum (V)].

Objective: To study the chemical constituents in roots of Peucedanum praeruptorum from Henan.

Method: The constituents were isolated by column chromatography on silica gel and ODS, and identified by NMR, MS spectroscopic methods.

Result: Six compounds, Pd-I b(1), marmesinsin (2), rutarin (3), isorutarin (4), 4H-1-benzopyran-4-one, 5-hydroxy-6-methoxy-2-phenyl-7-O-alpha-D-glucuronyl methyl ester (5), 4H-1-benzopyran-4-one, 5-hydroxy-6-methoxy-2-phenyl-7-O-alpha-D-glucuronyl acid (6) were isolated and identified.

[Regularity of changes in main active components of Schisandra chinensis before and after being processed with vinegar].

Objective: To investigate the regularity of changes in the main active components of Schisandra chinensis preparations before and after being processed with vinegar.

Method: High performance liquid chromatography was used to analyze the changes in the content of lignans and organic acids in S. chinensis preparations before and after being processed with vinegar.

Two new anthraquinone glycosides from the roots of Rheum palmatum.

Two new anthraquinone glycosides, named 1-methyl-8-hydroxyl-9,10-anthraquinone-3-O-β-D-(6'-O-cinnamoyl)glucopyranoside (1) and rhein-8-O-β-D-[6'-O-(3''-methoxyl malonyl)]glucopyranoside (2), have been isolated from the roots of Rheum palmatum, together with seven known compounds, rhein-8-O-β-D-glucopyranoside (3), physcion-8-O-β-D-glucopyranoside (4), chrysophanol-8-O-β-D-glucopyranoside (5), aleo-emodin-8-O-β-D-glucopyranoside (6), emodin-8-O-β-D-glucopyranoside (7), aleo-emodin-ω-O-β-D-glucopyranoside (8), and emodin-1-O-β-D-glucopyranoside (9). Their structures were elucidated on the basis of chemical and spectral analysis.

Study of analgesic and anti-inflammatory effects of lappaconitine gelata.

Objective: To explore the analgesic and anti-inflammatory effects of lappaconitine gelata (LA).

Methods: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate method in the mouse, and the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were used for investigation on the analgesic and anti-inflammatory effects of LA.

Results: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate methods was significantly inhibited by LA.

[Isolation-preparation and determination of chromones from Saposhnikovia divaricata].

Objective: To compare the contents of chromones in the different isolation and purification procedures from Saposhnikovia divaricata.

Method: The separation of six chromones was determined simultaneously by HPLC on a Kromasil C18 column at 35 degrees C with the methanol-0.1% phosphoric acid in gradient elution as the mobile phrase.

[Content comparison of diterpenoid pigments in different processed products of Gardenia jasminoides].

Objective: To compare the contents of diterpenoid pigments in the different processed products of Gardenia jasminoides.

Method: The separation of Crocin 1, Crocin 2, Crocin 3, Crocetin were determined simultaneously by HPLC on a kromasil C18 column at 35 degrees C with the m methanol-acetonitrile-0.3% formic acid anhydrous in gradient elution as the mobile phrase.

[Comparative studies on contents of iridoid in processed products from Gardenia jasminoides].

Objective: To compare the contents of iridoid in the different processed products from Gardenia jasminoides.

Method: Contents of geniposide and genipin gentiobioside in products were determined simultaneously by HPLC. A kromasil C18 column at 35 degrees C was used with the acetonitrile-0.

[Studies on expectorant compounds in volatile oil from root and rhizome of Aster tataricus].

Objective: To research the expectorant components in volatile oil from the root and rhizome of Aster tataricus.

Method: GC-MS was applied to isolate and identify the compounds. In addition, TLC was used to isolate compound, and its structure was elucidated on the basis of spectral data analysis.

[Studies on chemical constituents in fruit of Gardenia jasminoides].

Objective: To study the chemical constituents in Gardenia jasminoides.

Method: The constituents were isolated by column chromatography on silica gel and ODS, and identified by NMR, MS spectroscopic methods.

Result: Nine compounds, imperatorin (1), isoimperatorin (2), crocetin (3), 5-hydroxy-7, 3', 4', 5'-tetrainethoxyflavone (4), 2-methyl-3, 5-dihydroxychromone (5), sudan III (6), geniposide (7), crocin (8), crocin-3 (9) were isolated and identified.

[Identification of jizhi syrup using HPLC fingerprint].

Objective: To establish a HPLC fingerprint for quantitative analysis of the active constituents of jizhi syrup.

Method: HPLC analysis was performed on a Zorbax Sb C18 column (4.6 mm x 250 mm, 5 microm), the mobile phase in gradient elution was composed of (A) 1% acetic acid solution (including 0.

[Advances in studies on Platycodon grandiflorum].

Platycodon grandiflorum, as the traditional Chinese medicine, has been employed for dispersing the lung and resolving phlegm soothing the throat, and promoting pus discharge in ancient days. Triterpenoids are its main effective constituents which have dominant activities on antitussive, expectorant, antitumor, antioxidant and immune enhancement. This paper has mainly reviewed the progress of P.

[Studies on GC fingerprint of volatile oil of Houttuynia cordata].

Objective: To establish a GC fingerprint of the volatile oil of Houttuynia cordata.

Method: The volatile oil was extracted from H. cordata by water stream distillation method, and analyzed by GC coupled with FID.

[Study on transdifferentiation of renal tubular cells in rat chronic renal interstitial fibrosis induced by Radix Aristolochiae Fangchi Extract].

Objective: To investigate the relationship between renal tubular cells transdifferentiation and chronic renal interstitial fibrosis induced by Fangchi Extract in rat.

Method: The chronic renal interstitial fibrosis rat model was made by giving Radix Aristolochiae Fangchi extract (RAFE) and aristolichic acid (AA) respectively to rats through infusing stomach about 22 weeks discontinuously. Through immunnal histochemistry methods, investigating the expression of symbol proteins: Cytokine( CK) , alpha-Smooth muscle actin ( alpha-SMA) and Vimentin, and also the important fibrosis inducing factor-Transforming growth factor-beta (TGF-beta1 )on renal tubular cells.

[Studies on chemical constituents from roots of Peucedanum praeruptorum II].

Objective: To isolate and identify the chemical constituents from the roots of Peucedantu praeruptorum.

Method: The constituents were isolated by column chromatography on silica gel and ODS, and identified by NMR, MS spectroscopic methods.

Result: Eight compounds, (-) sclerodin (1), palmitic acid (2), (+)-praeruptorin E (3), bergapten (4), imperatorin (5), 2,6-dimethyl quinoline (6), tetracosanoic acid (7), and daucosterol (8), were isolated and identified.

[Studies on the chemical constituents in stem rind of Wikstroemia indica].

Objective: To study the chemical constituents in stem rind of Wikstroemia indica.

Method: The constituents were isolated by column chromatographies with silica gel and ODS, and identified by NMR, MS spectra.

Result: Six compounds, daphnoretin-7-O-beta-D-glucoside (1), quercitin (2), physcion (3), kaempferol 3-rutinoside (4), D-primev-ersyl genkwanine (5), and anabellamide (6) were isolated and identified.

[Studies on chemical constituents in roots of Heracleum rapula].

Objective: To study the chemical constituents in roots of Heracleum rapula.

Method: The constituents were isolated by column chromatography on silica gel and ODS, and identified by spectroscopic methods.

Result: Eight compounds, xanthotoxol (I), 8-geranyloxypsoralen (II), (+)-marmesin (III), beta-sitosterol (IV), stigmasterol (V), oleanolic acid (VI), ferulic (VII), scopoletin (VIII) were isolated and identified.

[Studies on chemical constituents in roots of Heracleum rapula].

Objective: To study the chemical constituents in roots of Heracleum rapula.

Method: The constituents were isolated by column chromatography on silica gel and ODS, and identified by spectroscopic methods.

Result: Nine compounds, osthol ( I ), bergapten (II), xanthotoxin (III), isopimpinellin (IV), imperatorin (V), isoimperatorin (VI), cnidilin (VII), phellopterin (VIII), rivulobirin A (IX) were isolated and identified.

[Determination of four components in root of Saposhnikovia divaricata by HPLC gradient elution].

Objective: To develop an HPLC method for determination of components in root of Saposhnikovia divaricata.

Method: The separation of four components was achieved on a reversed-phase Alltima C18 column with MeOH-H2O gradient elution at a flow rate of 1.0 mL x min(-1).