Publications by authors named "Yong-qin Chen"
Objective: The study established a nomogram based on quantitative parameters of spectral computed tomography (CT) and clinical characteristics, aiming to evaluate its predictive value for preoperative lymphovascular invasion (LVI) in gastric cancer (GC).
Methods: From December 2019 to December 2021, 171 patients with pathologically confirmed GC were retrospectively collected with corresponding clinical data and spectral CT quantitative data. Patients were divided into LVI-positive and LVI-negative groups based on their pathological results.
Article Synopsis
- The study investigates how the binding strength of the SARS-CoV-2 spike protein's receptor binding domain (RBD) to human ACE2 changes among four Omicron subvariants compared to the wild type.
- Molecular dynamics simulations show that the RBDs of Omicron subvariants display increased structural fluctuations and different binding affinities due to variations in electrostatic interactions.
- Key findings reveal that specific mutations, particularly Q493R, significantly enhance binding affinity, while the absence of this mutation in BA.4/5 leads to the weakest interaction with ACE2.
Aim: To investigate the protective effects of budesonide against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in a murine model and its underlying mechanism.
Methods: Adult male C57BL/6 mice were divided into three groups: control, ALI, and ALI + budesonide groups. LPS (5 mg/kg) was intratracheally injected to induce ALI in mice.
Article Synopsis
- A pot experiment examined the effect of nano zeolite (NZ) and ordinary zeolite (OZ) on the growth and Cd levels in two Chinese cabbage varieties, showing enhanced growth and antioxidant enzyme activity.
- The use of zeolite significantly lowered Cd concentrations in both the shoots and roots, with greater reductions observed at higher application levels, particularly under low and high Cd conditions.
- Nano zeolite treatments led to more substantial decreases in Cd levels compared to ordinary zeolite, highlighting the potential of zeolite application for safer vegetable production in contaminated soils.
Incubation experiments were carried out to investigate the influence of different nano zeolite(NZ) and ordinary zeolite(OZ) levels(0, 5, 10 and 20 g·kg) on the fraction distribution coefficient (FDC) of Cd and soil CEC at different soil pH (4, 5, 6, 7 and 8) when exposed to different cadmium(Cd) levels(1, 5, 10 and 15 mg·kg), and pot experiment were carried out to investigate the effects of nano zeolite(NZ) and ordinary zeolite(OZ) on the growth, Cd concentration and Cd accumulation of Chinese cabbage. The results showed that nano zeolite and ordinary zeolite decreased the concentration and FDC of exchangeable Cd (EX-F), and increased the concentration and FDC of carbonate(CAB-F), Fe-Mn oxide(FMO-F), organic matter (OM-F) and residual fraction(RES-F) in incubation experiments. At the end of incubation, the FDC of soil exchangeable Cd decreased from 72.
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- The research tested how ryegrass and arbuscular mycorrhizal treatments affect growth and cadmium (Cd) absorption in two tomato varieties, leading to notable increases in plant dry weights based on the treatments used.
- The study found that soil health improved with treatments, as indicated by higher microbial counts and enzyme activities, with differences observed between the two tomato varieties.
- The presence of treatments helped lower cadmium concentrations in various tomato parts, with "Luobeiqi" showing less accumulation of Cd compared to "Defu mm-8."
Incubation experiments were carried out to investigate the influence of different nano zeolite (NZ) and ordinary zeolite (OZ) levels(0, 5, 10 and 20 g · kg⁻¹) on the change trends in fraction distribution coefficient (FDC) of Cd when exposed to different Cadmium (Cd) levels (1, 5, 10 and 15 mg · kg⁻¹), and pot experiments were carried out to investigate their influence on soil Cd fraction and Cd uptake by cabbage. The results in incubation experiments showed that the application of nano zeolite as well as ordinary zeolite effectively decreased the FDC of exchangeable Cd and increased the FDC of Fe-Mn oxide fraction. The FDC of soil Cd from 0 d to 28 d was deceased at first, then increased and tended to be stable, and finally increased.
View Article and Find Full Text PDF[Intragastric and subcutaneous administration of yolk antibodies against adipocyte plasma membrane proteins on growth and fat deposition in rats].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
May 2011
Article Synopsis
- The study examined how different methods of antibody administration affect growth and fat deposition in rats.
- Administration of antibodies via intragastric method reduced fat indices and serum triglycerides while enhancing free fatty acids, indicating improved body composition.
- In contrast, the subcutaneous method increased muscle index but had no significant effect on fat deposits, highlighting that intragastric administration was more effective overall.
Article Synopsis
- This study investigates the impact of incorporating FDG-PET scans into radiotherapy planning for patients with locally recurrent nasopharyngeal carcinoma, compared to standard CT scans.
- A total of 43 patients were analyzed, revealing that the use of FDG-PET led to better identification of tumor areas, with nearly 51% of patients showing inadequate coverage of the tumor when relying solely on CT.
- The findings suggest that FDG-PET can enhance treatment accuracy by providing a clearer delineation of the disease, reducing the risk of missing critical tumor areas in radiotherapy.
[Studies on plantlet regeneration from the mature leaves of Dioscorea zingiberensis].
Zhongguo Zhong Yao Za Zhi
February 2004
Objective: To establish a protocol of rapid clonal propagation of Dioscorea zingiberensis using mature leaves as explants.
Method: Out the optimal hormone combinations for callus induction, adventitious bud initiation, adventitious bud multiplication and rooting were found out by using MS medium with the macroelements at half strength as basal medium and studying the effects of BA, NAA and IBA on the processes.
Result And Conclusion: More than 80% of leaf explants formed callus when they were cultured on the media containing 1.