The Metabolomic Profiling of the Flavonoid Compounds in Red Wine Grapes and the Impact of Training Systems in the Southern Subtropical Region of China.

Flavonoids play an important role in forming wine grapes and wine quality characteristics. The flavonoids of three winter red wine grapes, Yeniang No. 2 (YN2), Marselan (Mar), and Guipu No.

[Analysis of Clinical Characteristics and Laboratory Indicators in Patients with Solid Malignant Tumor-Associated Venous Thromboembolism].

Objective: To analyze the clinical features and laboratory indicators in patients with solid malignant tumor-associated venous thromboembolism (Ta-VTE), and to study the risk factors for Ta-VTE.

Methods: The hospitalized patients with VTE in Guizhou Provincial People's Hospital from January to December 2020 were enrolled, and they were divided into Ta-VTE group and pure VTE group based on the presence or absence of solid malignant tumor. The differences in clinical data and laboratory indicators between the two groups were analyzed, and the indicators with significant differences were included in logistic regression model to analyze the risk factors of Ta-VTE.

[The mechanism of scutellarin inhibiting oral leukoplakia carcinogenesis based on network pharmacology and in vitro cytology].

Purpose: To investigate the potential mechanisms of scutellarin on oral leukoplakia (OLK) by network pharmacology and further verify by cytology.

Methods: The potential targets of scutellarin acting on OLK were excavated through network pharmacology. PPI network was constructed, and the possible targets and pathways of scutellarin were predicted by GO and KEGG enrichment analysis.

The significance of the microlymphangiogenesis, microangiogenesis, and combined detection of programmed cell death-1 protein (PD-1)/ki67 in gastric cancer tissues.

Purpose: To investigate the relationship between the microlymphangiogenesis, microangiogenesis, and combined detection of the programmed cell death-1 protein (PD-1)/ki67 in patients with gastric cancer as well as the disease prognosis.

Methods: Immunohistochemistry was used to detect the microlymphatic density (MLD) and microvessel density (MVD) in the central and peripheral zones in 92 cases of gastric cancer, along with the number of PD-1- and ki67-positive tumor cells.

Results: The central zone of the gastric cancer tissue contained fewer atretic cord-like lymphatic vessels than the peripheral zone, while the peripheral zone contained an increased number of lymphatic vessels compared with the central zone.

[The effect of osthole on lipopolysaccharide-induced macrophages polarization and inflammatory reaction].

Purpose: To investigate the effect of Osthole (OST) on lipopolysaccharide (LPS)-induced macrophage polarization and inflammatory reaction.

Methods: The effect of different concentrations of OST on proliferative activity of RAW264.7 macrophages was examined by CCK-8 method; the effect of OST at different concentrations (6.

MicroRNA-134 inhibits tumor stem cell migration and invasion in oral squamous cell carcinomas via downregulation of PI3K-Akt signaling pathway by inhibiting LAMC2 expression.

Background: Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the mouth. Some studies have found that multiple microRNAs (miRs) participate in OSCC physiological and pathological processes.

Methods: We explored the mechanism of action of miR-134 in OSCC involving the PI3K-Akt signaling pathway.

Identification of Empoasca onukii (Hemiptera: Cicadellidae) and Monitoring of its Populations in the Tea Plantations of South China.

Tea green leafhoppers (Empoasca spp.) are considered one of the major pests in tea plantations in Asia. They are, however, difficult to monitor due to their size and flying and jumping abilities.

[Optimize visiting sequence and time-interval appointment of re-visiting patients in stomatology].

Purpose: To optimize visiting sequence and time-interval appointment mode to reduce waiting time of re-visiting patients in department of stomatology based on clinical data repository.

Methods: Waiting time data of re-visiting patients in department of stomatology was collected and divided into 2 groups. A total of 70897 patients from July 2014 to September 2014 were enrolled as experimental group (group year-2014), while 63960 patients from July 2013 to September 2013 were used as control group (group year-2013).

Deficient zinc levels and myocardial infarction : association between deficient zinc levels and myocardial infarction: a meta-analysis.

The purpose of this study is to clarify the association between Zn levels and myocardial infarction (MI) using a meta-analysis approach. We searched articles in the PubMed, OVID, and ScienceDirect published as of November 2014. Thirteen eligible articles with 2886 subjects from 41 case-control studies were identified.

[Optimize the service flow of stomatological department to accommodate outpatient's demands].

Purpose: To provide measures to dispose of unsatisfactory service links for outpatients, and to optimize the service flow of department of stomatology.

Methods: Four hundred and seventy-nine questionnaires were delivered in Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine. The questionnaires included 15 questions relating to general experience in department of stomatology and assessment on separate link of service flow.

[Observation on curative effect of thermal acupuncture needle muscular stimulation therapy for knee osteoarthritis patients].

Objective: To observe the therapeutic effect of thermal acupuncture needle muscular stimulation for treatment of knee osteoarthritis patients.

Methods: A total of 120 outpatients with knee osteoarthritis were randomly and equally divided into control and treatment groups. Patients of the treatment group were treated by inserting the acupuncture needles into the attached sites of the quadriceps femoris, musculus vastus medialis, vastus lateralis, etc.

[Study on the expression and potential effect of PD-L1mRNA and PD-L2mRNA in oral lichen planus].

Purpose: To study the expression of PD-L1 and PD-L2mRNA in oral lichen planus(OLP) patients' peripheral blood and focal mucosa, and the different expression of target molecules in gene level in different clinical and pathological OLP groups.

Methods: The expression of PD-L1 and PD-L2 mRNA in OLP patients, which included 35 reticular and 25 atrophic-erosive OLP patients, 38 cases without dysplasia and 22 cases with dysplasia, was examined by real-time PCR. Peripheral blood and mucosa from 10 volunteers were used as control.

A clinicopathological study on verrucous hyperplasia and verrucous carcinoma of the oral mucosa.

Background: Oral verrucous hyperplasia (VH) and verrucous carcinoma (VC) are two clinicopathologically distinctive oral verrucous lesions. The objective of this study was to investigate the clinicopathological features of the two verrucous lesions and estimate their relationship from China.

Methods: Retrospective review of two series of patients with histologically confirmed VH (n = 121) and VC (n = 56) between 1996 and 2009 in our hospital were conducted.

The high expression level of programmed death-1 ligand 2 in oral lichen planus and the possible costimulatory effect on human T cells.

Background: Oral lichen planus (OLP) is a T-cell-mediated chronic autoimmune disease whose precise etiology is unknown. The recently identified costimulatory programmed death-1 (PD-1) molecule and its ligands, PD-L1 and PD-L2, have been identified as CD28-B7 family molecules and constitute a regulatory pathway of potential therapeutic use in immune-mediated diseases.

Methods: We examined the expression of two ligands of PD-1 at both the protein and gene level in the focal mucosa and peripheral blood of OLP patients using immunohistochemistry and real-time PCR.

[T cell receptor BV gene preferential usage in oral lichen planus].

Purpose: To identify the T cell receptor (TCR) structural characteristics of infiltrating T cells derived from the lesional tissues of oral lichen planus (OLP) patients.

Methods: BV gene distribution analysis was performed quantitatively in OLP patients using real-time polymerase chain reaction. The data was analyzed by Mann-Whitney U test using GraphPad Prism version 5.

[In vitro activity of matrine against Candida albicans biofilms].

Purpose: To establish a model of Candida albicans biofilms and to examine the effect of matrine on C.albicans biofilms and ultrastructure.

Methods: C.

[Clinical and pathologic features of malignant myoepithelioma of salivary glands].

Objective: To analyze the clinical features, morphology and biologic behavior of primary malignant myoepithelioma (MME) of salivary glands.

Methods: The H&E sections of 16 MME cases were reviewed. Immunohistochemical study using EnVision method for cytokeratin (CK), epithelial membrane antigen (EMA), vimentin, S-100 protein, desmin, muscle-specific actin (MSA), smooth muscle actin (SMA), Myo, proliferation cell nuclear antigen (PCNA), leukocyte common antigen (LCA) and glial fibrillary acidic protein (GFAP) was carried out.