Publications by authors named "Yong-li Lu"
[Research advances in the calculating method of nitrogen use efficiency (NUE) in cultivated lands].
Ying Yong Sheng Tai Xue Bao
July 2015
Article Synopsis
- Nitrogen use efficiency (NUE) is crucial for assessing nitrogen use and improving fertilization practices in agriculture, especially in the context of environmental concerns.
- Recent research highlights the variations and low values of NUE in China, prompting discussions about its traditional calculation methods and the need for more effective substitutes.
- The paper advocates for developing a comprehensive evaluation system for nitrogen utilization that aligns with China's agricultural realities, emphasizing the interrelationships between nitrogen application rates, crop yields, and nitrogen loss.
[Effects of different potassium fertilizer application periods on the yield and quality of Fuji apple].
Ying Yong Sheng Tai Xue Bao
April 2015
Article Synopsis
- A study was conducted to evaluate how different timing of potassium fertilizer application affects apple production, including yield, fruit quality, and nutrient levels.
- Results showed that applying potassium significantly increased apple yield (by 4.3%-33.2%) and improved fruit quality compared to no potassium treatment.
- The best results were seen with split applications of potassium at the flowering and fruit enlargement stages, which enhanced yield and quality but lowered calcium levels in the fruit, potentially impacting quality.
Article Synopsis
- Recent research from Chinese scholars has focused on improving the methods for calculating nitrogen use efficiency (NUE) in cultivated lands, particularly in wheat-maize rotation systems.
- The study found that traditional subtraction methods for calculating NUE separately for wheat and maize seasons are flawed due to significant differences in soil fertility between plots over time.
- The cumulative NUE calculation method provided a more accurate representation of nitrogen utilization by treating the wheat and maize seasons as a whole, resulting in smaller values and variations compared to traditional methods, while the soil N balance method yielded the largest NUE values but lacked reliability.
Article Synopsis
- Aluminum, a neurotoxin linked to Alzheimer's disease (AD), was shown to cause brain changes similar to AD, including tau hyperphosphorylation in mice.
- Ginsenoside Rb1, an active component in ginseng, demonstrated neuroprotective effects by improving cognitive function and decreasing tau hyperphosphorylation in mice previously exposed to aluminum.
- The study suggests that Rb1's protective mechanism involves regulation of specific proteins (p-GSK3 and PP2A), positioning it as a potential preventive treatment for Alzheimer's and related neurodegenerative diseases.
Excessive accumulation of β-amyloid (Aβ) has been proposed as a pivotal event in the pathogenesis of Alzheimer's disease. Possible mechanisms underlying Aβ-induced neuronal cytotoxicity include oxidative stress and apoptosis. Reactive oxygen species (ROS) have been proposed to be involved in the apoptotic mechanism of Aβ-induced cytotoxicity.
View Article and Find Full Text PDFObjective: To investigate effects of K(ATP) opener on the expressions of caspase-12 mRNA and protein, and to explore the role of endoplasmic reticulum (ER) stress pathway in the mechanism of K(ATP) opener protecting against neuronal apoptosis after cerebral ischemia-reperfusion.
Methods: Two hundred rats were randomly divided into four groups: sham operation group, ischemia-reperfusion group, K(ATP) opener group, and K(ATP) blocker group. The middle cerebral artery occlusion (MCAO) model was established by intraluminal suture occlusion method; neuronal apoptosis was detected by TUNEL staining.
Cannabinoids inhibit ATP-activated currents in rat trigeminal ganglionic neurons.
Sheng Li Xue Bao
December 2007
The present study aimed to investigate whether cannabinoids could modulate the response mediated by ATP receptor (P2X purinoceptor). Whole-cell patch-clamp recording was performed on cultured rat trigeminal ganglionic (TG) neurons. The majority of TG neurons were sensitive to ATP (67/75, 89.
View Article and Find Full Text PDFObjective: To investigate effect of pinacidil, an ATP sensitive potassium channel (K(ATP)) opener, on the neuronal apoptosis and its signaling transduction mechanism following focal cerebral ischemia-reperfusion in rats.
Methods: One hundred male Wistar rats were randomly divided into four groups: A, sham-operated group; B, ischemia-reperfusion group; C, K(ATP) opener treatment group; and D, K(ATP) opener and blocker treatment group. The middle cerebral artery occlusion (MCAO) model was established by using the intraluminal suture occlusion method, neuronal apoptosis was determined by TUNEL staining, and expressions of caspase-8, caspase-9 and caspase-3 mRNA were detected by in situ hybridization.
[Protective effect of ATP sensitive potassium channel opener on cerebral ischemia/reperfusion injury and its signal transduction mechanism].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
April 2007
Objective: To study the protective effect of ATP sensitive potassium channel(K( ATP))opener against neuronal apoptosis following focal cerebral ischemia/reperfusion (I/R) and its signal transduction mechanism.
Methods: Two hundred male Wistar rats were randomly divided into four groups: sham operation group (A group), I/R group (B group), K( ATP) opener treatment group (C group) and K( ATP) opener and blocker treatment group (D group). The middle cerebral artery occlusion (MCAO) by intraluminal suture method was used to reproduce cerebral ischemia, and perfusion was restored 2 hours after MCAO.
Aim: To investigate the effect of aluminum (Al) on high voltage-dependent calcium current (I(HVA)) and its modulation by ginkgolide B (Gin B).
Methods: The whole-cell, patch-clamp technique was used to record IHVA from acutely isolated hippocampal CA1 pyramydal neurons in rats.
Results: Al 0.