Epstein-Barr virus-positive iris diffuse large B-cell lymphoma detected by metagenomic next-generation sequencing.

Purpose: Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (DLBCL) is a relatively rare subtype of DLBCL. Herein, we report a case of a patient with EBV-positive iris DLBCL after undergoing penetrating keratoplasty and discuss its possible pathogenesis.

Methods: A 72-year-old male patient presented to our hospital with progressive blurring of vision in the left eye for the past 4 months.

Single centre analysis of factors influencing surgical treatment of splenic trauma in children.

Objective: This study aims to investigate determinants impacting the surgical management of splenic trauma in paediatric patients by scrutinizing age distribution, etiological factors and concomitant injuries. The analysis seeks to establish a foundation for delineating optimal operative timing.

Methods: A cohort of 262 paediatric cases presenting with splenic trauma at our institution from January 2011 to December 2021 underwent categorization into either the conservative or operative group.

Vitrectomy with residual internal limiting membrane covering and autologous blood for a secondary macular hole: A case report.

Background: Myopic foveoschisis (MF) is a common complication of pathological myopia. A macular hole (MH) usually results from the natural progression of MF and is a common complication of vitrectomy. Vitrectomy combined with residual internal limiting membrane (ILM) covering and autologous blood was effective for closing a secondary MH.

Choroidal metastasis with retinal detachment: A case report.

Rationale: Breast carcinoma is the most common primary source of choroidal metastasis (CM). In the present case, esophageal cancer was the primary tumour, brain metastasis occurred, and CM occurred later in the left eye with 2 retinal detachments, which is very rare.

Patient Concerns: A 62-year-old man complained of a sudden decrease in visual acuity consisting of a small shadow in front of his left eye with a sensation of covered vision after 1 cycle of systemic chemotherapy and radiotherapy for resected esophageal cancer with brain metastasis.

Probing the structural, electronic and magnetic properties of AgSc (n = 1-16) clusters.

The structural, electronic and magnetic properties of AgnSc (n = 1-16) clusters have been studied on the basis of density functional theory and the CALYPSO structure prediction method. The optimized geometry exhibits that the growth process of Sc-doped silver clusters have a periodic structural change. The Ag atom grows around a basically invariant cluster core in each growth cycle.

Probing the Structural, Electronic, and Magnetic Properties of Ag V (n = 1-12) Clusters.

The structural, electronic, and magnetic properties of Ag V (n = 1-12) clusters have been studied using density functional theory and CALYPSO structure searching method. Geometry optimizations manifest that a vanadium atom in low-energy AgV clusters favors the most highly coordinated location. The substitution of one V atom for an Ag atom in Ag (n ≥ 5) cluster modifies the lowest energy structure of the host cluster.

Primary angle-closure glaucomas disturb regional spontaneous brain activity in the visual pathway: an fMRI study.

Objective: To explore the underlying regional brain activity deficits in the visual cortex in patients with primary angle-closure glaucoma (PACG) relative to normal controls (NCs) using regional homogeneity (ReHo) method, and its relationship with behavioral performances.

Patients: Twenty PACG patients (10 females, 10 males; mean age ± standard deviation [SD]: 54.42±9.

The compromised inflammatory response to bacterial components after pediatric cardiac surgery is associated with cardiopulmonary bypass-suppressed Toll-like receptor signal transduction pathways.

Purpose: Cardiopulmonary bypass (CPB) during pediatric cardiac surgery often elicits a systemic inflammatory response followed by a compromised immune response, which has been attributed to the morbidity of postoperative infection; however, the underlying mechanism(s) has not yet been fully elucidated. We hypothesized that CPB inhibits the activation of Toll-like receptor (TLR) signal transduction pathways, thereby causing an immunosuppressive state after pediatric cardiac surgery.

Methods: We examined 20 children with congenital heart disease undergoing pediatric cardiac surgery.

Development of a rabbit corneal equivalent using an acellular corneal matrix of a porcine substrate.

Purpose: The tissue equivalent that mimics the structure and function of normal tissue is a major bioengineering challenge. Tissue engineered replacement of diseased or damaged tissue has become a reality for some types of tissue such as skin and cartilage. The tissue engineered corneal epithelium, stroma, and endothelium scaffold are promising concepts in overcoming the current limitations of a cornea replacement with an allograft.

[Morphologic characteristics and formation of adhesion complex of cultured rabbit limbal epithelium on amniotic membrane in vitro].

Objective: To investigate the morphologic characteristics and the formation of adhesion complex formation of cultured rabbit limbal epithelium on amniotic membrane in vitro.

Methods: The limbal explants (size: 2 mm x 2 mm) were taken from 15 rabbits and were treated with 1.2 U/ml dispase II at 37 degrees C in 5% CO(2) incubator for 20 min, then, cultured on amniotic membrane in vitro for 4 weeks.

Change of proliferation rate of corneal epithelium in the rabbit with orthokeratology lens.

Objective: To investigate the cell proliferation rate of normal corneal epithelium with extended orthokeratology lens (OKL) wear in comparison with extended rigid gas-permeable (RGP) lens wear.

Methods: Twenty-four rabbits were fitted unilaterally with either an OKL or an RGP lens, and the other eye was used as a control. They were injected with 5-bromo-2-deoxyuridine (BrdU) 24 h prior to being sacrificed.