Publications by authors named "Yong-fang Wang"

Ecological drought monitoring is important for regional status assessment and protection of water resources. In this study, we constructed a new ecological drought index, the kernel temperature vegetation drought index (kTVDI), by using the kernel normalized vegetation index (kNDVI) to improve the temperature vegetation drought index (TVDI) in Inner Mongolia. We further analyzed the spatial and temporal distribution of ecological drought in Inner Mongolia during 2000-2022 and the future trend of ecological drought by using segmented linear regression model, Theil-Sen median, Mann-Kendall test, and Hurst index.

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Bacterial meningitis is a serious complication after neurosurgery and has a high mortality rate. Early diagnosis and timely treatment are crucial or will have disastrous consequences. The classic triad of bacterial meningitis lacks sensitivity and specificity.

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Article Synopsis
  • The study investigates Tripterygium wilfordii polyglycosides (TWP), a traditional Chinese medicine known for its anti-inflammatory and immunosuppressive effects, particularly in treating autoimmune skin diseases like psoriasis, systemic lupus erythematosus, and pemphigus.* -
  • Researchers utilized network pharmacology to identify potential targets and mechanisms of TWP, analyzing numerous databases to understand both its therapeutic benefits and possible liver toxicity associated with long-term use.* -
  • Results revealed 41 shared targets for TWP's effects on autoimmune diseases, highlighting the IL-17 signaling pathway's significance, and experimental models confirmed TWP's efficacy in reducing inflammation and improving skin conditions.*
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Taking the Mongolian Plateau as the study area, the MODIS normalized difference vegetation index (NDVI) and the land surface temperature (LST) in the growing season from 2000 to 2019 were used to construct the NDVI-LST feature space, and based on which the temperature vege-tation dryness index (TVDI) of the Mongolian Plateau was calculated. We used Theil-Sen Median trend analysis, Mann-Kendall test, and Hurst index method to analyze the spatial and temporal varia-tions and future trends of TVDI on the Mongolian Plateau. Furthermore, we examined the relationship between meteorological factors and TVDI on the Mongolian Plateau using partial correlation analysis.

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Aim: To develop a novel rat model of heterogeneous hepatic injury.

Methods: Seventy male Sprague-Dawley rats were randomly divided into a control group ( = 10) and a colchicine group ( = 60). A 0.

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The corn in the grain filling stage fell over in the central region of Jilin province by the Typhoon Bolaven influence. In order to determine the impact of falling over corn canopy on the reflected information, the hyperspectral reflectance was detected at different viewing zenith angles, at the same time, the polarized reflection was also measured. The results from the analysis by combining the reflection and polarization from corn canopy showed that the reflection of falling over corn is low in visible, while increases in the near infrared wavelength.

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Aim: To investigate the distribution of killer cell immunoglobulin-like receptor (KIR) and its specific ligand human leukocyte antigen (HLA) in Jiangsu Han population.

Methods: 173 samples from unrelated healthy individuals of Jiangsu Han population were genotyped and observed for KIR, HLA-Cw and HLA-Bw4 using a SYBR Green I real-time PCR and PCR-SSP method, respectively. The number and type of KIR/HLA pairs inherited in each individual were analyzed.

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Aim: To develope a novel real-time PCR method for KIR genotyping.

Methods: KIR genotyping is performed using 16 real-time PCR reactions, each containing two-three KIR-specific primers, a pair of internal positive control primers and a fluorescence dye, SYBR Green I. By the analysis of the Tm and the characteristic of the melting curve of the amplified products, we identified the presence or absence of 16 KIR genes.

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Aim: To investigate immune effect in mice on the basis of BCG priming and DNA vaccine boosting, and to provide a new strategy for development of new type of anti-tuberculosis DNA vaccine further.

Methods: After mice were inoculated with BCG of 1x10(6) clone formation unit each three weeks, 100 microg of DNA vaccine was injected intramuscularly in mice two times at 3 week intervals. The proliferative responses of murine cytotoxic T lymphocytes (CTL), natural killer (NK) and spleen cell to antigen 85A(Ag85A) were measured by MTT method respectively.

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Aim: To explore the anti-tumor mechanism of Sp2/0-mIL-21 tumor vaccine in mice.

Methods: The molecules of MHC-I and CD80 on the surface of Sp2/0-mIL-21 tumor vaccine were detected by flow cytometry (FCM) respectively. A flow cytometric CFSE-7-AAD cytotoxicity assay was used to detect the cytotoxic activities of NK cells and CTLs.

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Objective: To assess the safety of dietary arsenic intakes in different areas in China.

Methods: Using the total dietary study method, the analytical samples were obtained in different areas by food consumption survey, food aggregation, food sampling and preparation. The levels of dietary total and inorganic arsenic were determined by the hydride generation atomic absorption spectrometry and atomic fluorospectrophotometry.

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