Publications by authors named "Yong-an Xu"

Background: Trauma-induced coagulopathy (TIC) due to serious injuries significantly leads to increased mortality and morbidity among elderly patients. However, the risk factors of TIC are not well elucidated. This study aimed to explore the risk factors of TIC in elderly patients who have major trauma.

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Aim: This study aimed to investigate the associations of serum lactate level [within and after 24 h of the intensive care unit (ICU) admission] and lactate clearance rate with delirium and assess associations of lactate and lactate clearance rate with 30-day mortality in delirium patients.

Methods: Data in this retrospective cohort study were extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database in 2012-2019. The associations of lactate and lactate clearance rate with delirium were explored through univariable and multivariable logistic regression analyses, whereas the associations of lactate and lactate clearance rate with 30-day mortality in delirium patients were investigated using univariable and multivariable Cox regression analyses.

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Article Synopsis
  • Following the withdrawal of paraquat, diquat (DQ) has become the main herbicide, but it poses serious risks, including a poisoning mortality rate of up to 50%.
  • DQ poisoning can range from mild to fulminant, the latter often leading to multiple organ failure within 48 hours, complicating clinical treatment.
  • Research indicates that DQ may damage endothelial cells (EC), which are crucial for blood circulation in sensitive organs, and the authors suggest this EC damage could be a key factor in the severe organ failure associated with DQ poisoning.
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Trauma is a life-threatening "modern disease". The outcomes could only be optimized by cost-efficient and prompt trauma care, which embarks on the improvement of essential capacities and conceptual revolution in addition to the disruptive innovation of the trauma care system. According to experiences from the developed countries, systematic trauma care training is the cornerstone of the generalization and the improvement on the trauma care, such as the Advance Trauma Life Support (ATLS).

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This experiment was conducted to investigate the remediation effects of bio-conditioners vermicompost (VC) and biochar (BC) on cadmium contaminated soil under the threat of acid rain, individually and associatively. With the application of soil conditioners, the percentages of HOAc-extractable Cd decreased 5.2-6.

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Objective: To optimize the methods of isolating human eccrine sweat gland cells in vitro so as to get efficiently primary human sweat glands.

Methods: The fresh and normal skin tissue was cut into pieces of microskin about 1mm3 and the following 3 group digestion buffer was applied to isolated gland cells. The digestion buffer of group A was the equivoluminal mixture of Trypsin-Ethylene Diamine Tetraacetic Acid (EDTA) and collagenase-II (2 mg/ml).

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Background: This study aimed to evaluate the effects of standard rescue procedure (SRP) in improving severe trauma treatments in China.

Methods: This study was conducted in 12 hospitals located in geographically and industrially different cities in China. A standard procedure on severe trauma rescue was established as a general rule for staff training and patient treatment.

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Objective: To study the indicators and validity of inquiry in the screening of chronic schistosomiasis japonica.

Methods: 51 villages of Hanshou county were selected at random in Hunan Province and the whole resident (>6 months/year) population aged 5 years and above was eligible for inclusion in the study. Inquiry through questionnairing, serological test (ELISA) and B type ultrasonography were applied respectively to screen chronic cases and evaluate morbidity due to schistosome infection.

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