Publications by authors named "Yong-Zhi Zhuang"
Article Synopsis
- The article discusses the challenges of treating intrahepatic cholangiocarcinoma (iCCA), as most patients do not respond well to existing therapies and highlights ongoing efforts to find new molecular targets.
- It focuses on a study by Tang which examines the role of the PSMD6 gene in iCCA cells, finding it crucial for cell proliferation and overexpressed in iCCA tissues, although the study has limitations regarding its methods and insights into mechanisms.
- The editorial also mentions recent advancements in targeted drug therapies and immunotherapies for iCCA, and underscores the potential of CRISPR technology and other computational methods in cancer research.
Background: Prospective real-life data on the safety and effectiveness of rituximab in Chinese patients with diffuse large B-cell lymphoma (DLBCL) or follicular lymphoma (FL) are limited. This real-world study aimed to evaluate long-term safety and effectiveness outcomes of rituximab plus chemotherapy (R-chemo) as first-line treatment in Chinese patients with DLBCL or FL. Hepatitis B virus (HBV) reactivation management was also investigated.
View Article and Find Full Text PDFThe complete mitochondrial genome sequence and mutations of the lung cancer model inbred rat strain (Muridae; Rattus).
Mitochondrial DNA A DNA Mapp Seq Anal
September 2016
We reported the complete mitochondrial genome sequencing of an important Lung cancer model inbred rat strain for the first time. The total length of the mitogenome was 16,312 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region.
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