Publications by authors named "Yong-Yi Xu"
Introduction: Transcutaneous electrical acupoint stimulation (TEAS) has been proposed for postoperative urinary retention (POUR). This meta-analysis evaluated the effect of TEAS in preventing POUR.
Methods: Databases were searched until February 6, 2023.
Objective: This systematic review and meta-analysis aimed to evaluate the preventive effect of transcutaneous electrical acupoint stimulation on postoperative delirium in elderly surgical patients.
Methods: PubMed, CENTRAL, China National Knowledge Infrastructure, and WanFang databases were searched for randomized controlled trials regarding the effect of transcutaneous electrical acupoint stimulation on preventing postoperative delirium in elderly patients undergoing any type of surgery. The primary outcome was the incidence of postoperative delirium.
Background: Biosynthesis of leukotriene (LT) by arachidonic acid involves 5-lipoxygenase (5-LO) as an important precursor. Here, we evaluated the role of pseudohypericin (PHP) for its postulated 5-LO inhibitory activity along with a Cys-LT receptor antagonist zafirlukast (ZFL) against inflammatory response and tissue injury in mice.
Materials And Methods: The spinal injury was induced by two-level laminectomy of T6 and T7 vertebrae.
Activation of AMP-activated protein kinase by compound 991 protects osteoblasts from dexamethasone.
Biochem Biophys Res Commun
January 2018
Dexamethasone (Dex) induces direct cytotoxicity to cultured osteoblasts. The benzimidazole derivative compound 991 ("C991") is a novel and highly-efficient AMP-activated protein kinase (AMPK) activator. Here, in both MC3T3-E1 osteoblastic cells and primary murine osteoblasts, treatment with C991 activated AMPK signaling, and significantly attenuated Dex-induced apoptotic and non-apoptotic cell death.
View Article and Find Full Text PDFThis study investigated the mechanisms responsible for the neuroprotective effect of sildenafil citrate (SFC) on ischemia-reperfusion spinal cord (SC) injuries. Balloon occlusion of the thoracic aorta was used to induce SC ischemia. The animals (n=30) were separated into three groups: sham, SC injury with saline, and SC injury with 5mg/kg i.
View Article and Find Full Text PDF[Selection of suitable procedure in the treatment of degenerative lumbar scoliosis based upon imaging studies].
Zhonghua Yi Xue Za Zhi
January 2013
Objective: To compare the clinical efficacies of two different procedures in the treatment of degenerative lumbar scoliosis.
Methods: From August 2008 to August 2011, 28 patients of lumbar degenerative scoliosis were divided into one group (n = 14) undergoing modified transforaminal lumbar interbody fusion (TLIF) instrumented surgery and another group (n = 14) undergoing posterolateral fusion (PLF) instrumented surgery. There were 12 males and 16 females with a mean age of 66.
[Treatment of degenerative lumbar scoliosis via posterior decompression and fusion with internal fixation].
Zhonghua Yi Xue Za Zhi
November 2011
Objective: To explore the pathogenic mechanism, operative techniques and therapeutic efficacy of lumbar degenerative scoliosis.
Methods: A retrospective analysis was performed for 32 patients (14 males and 18 females with a mean age of 67.4 years old) with degenerative lumbar scoliosis undergoing posterior decompression and fusion with pedicle screw system from January 2007 to March 2010.
[Pedicle screw implanting in the treatment of multi-level lumbar spine fractures].
Zhonghua Yi Xue Za Zhi
January 2010
Objective: To review the clinical data of a group of patients with multi-level lumbar spine fractures treated with TSRH-3D pedicle screw system and to investigate the effect and post-operative efficacy of this technique.
Methods: Eighteen patients diagnosed as multi-level lumbar spine fracture were treated with TSRH-3D pedicle screw system. The operations were performed at 4 hours to 2 days after injury and the follow-up period was 15-32 months (mean: 23 months).