Publications by authors named "Yong-Xi Tong"
Article Synopsis
- * The model evaluated data from 914 suspected COVID-19 pneumonia cases, assessing variables like epidemiological features, clinical symptoms, and imaging results.
- * Results showed the model had a high accuracy of 87%, a sensitivity of 83.82%, and specificity of 89.57%, indicating its effectiveness for early detection and treatment of COVID-19 pneumonia.
Article Synopsis
- The study aimed to create a fast screening model to early detect novel coronavirus pneumonia (NCP) in a population from Zhejiang, China.
- It involved 880 individuals suspected of having NCP and utilized various predictors like epidemiological data, clinical signs, and lab results, achieving a high accuracy of 0.920.
- The developed models showed strong sensitivity and specificity, proving to be practical and cost-effective tools for predicting NCP early, especially amid a widespread outbreak.
Article Synopsis
- * The study analyzed the proteomic profiles of CHB patients with different levels of liver fibrosis to identify potential serum biomarkers for detecting the critical S2 stage, involving 90 CHB patients and additional validation groups.
- * A total of 139 proteins showed significant expression differences across fibrotic stages, with five candidates identified as promising biomarkers, particularly ficolin-2 (FCN2) and carboxypeptidase B2 (CPB2), which require further investigation for their
Article Synopsis
- Tuberculous meningitis (TBM) is a severe infection of the brain's protective membranes, with high rates of illness and death, making it difficult to diagnose against other meningitis types.
- Researchers conducted a study analyzing cerebrospinal fluid (CSF) samples from patients with TBM and other types of meningitis using advanced mass spectrometry to identify unique metabolites.
- The analysis revealed distinct metabolic profiles between TBM and other meningitis forms, uncovering potential biomarkers for better differentiation and diagnosis of TBM.
Article Synopsis
- Tuberculous meningitis (TBM) is a severe form of central nervous system tuberculosis with a notably poor prognosis, primarily assessed by the Glasgow Outcome Scale at discharge.
- A study of 45 TBM patients revealed that 77.8% had a good prognosis, while 22.2% faced a poor prognosis, with key factors such as old age, disturbed consciousness, and hydrocephalus linked to worse outcomes.
- Multivariate analysis identified old age and hydrocephalus as significant independent predictors of poor prognosis, highlighting the need for timely and special care for affected patients.
Article Synopsis
- Peliosis hepatis (PH) is a rare liver condition that features blood-filled cavities, making it difficult to distinguish from other types of liver lesions during imaging.
- The report discusses two cases where patients showed liver lesions on ultrasound and CT scans, without any previous liver issues or drug use.
- Diagnosing PH involved liver biopsy and laparoscopy, revealing sinusoidal dilatations, and both patients showed good recovery after follow-up for a year.
[Clinical significance of serum differential protein examination in chronic hepatitis B related liver fibrosis].
Zhonghua Gan Zang Bing Za Zhi
December 2010
Objective: To investigate the clinical significance of the expression of serum differential protein in patients with chronic hepatitis B (CHB) related liver fibrosis.
Methods: One hundred and ten CHB patients confirmed by liver biopsies were enrolled, 83 for modeling and 27 for verification. According to Ishak staging, 55 patients in the modeling group were with significant liver fibrosis ( F is more than or equal to 3 ) and 28 patients with normal/mild liver fibrosis ( F0-F2 ).
[Effects of N-acetylcysteine on serum IL-18 level in severe hepatitis patients].
Zhonghua Gan Zang Bing Za Zhi
November 2003