Publications by authors named "Yong-Sen Zhao"
Article Synopsis
- * The immunosensor operates on a "sandwich" principle, where the detection of CYFRA 21-1 results in a significant decrease in electrical current, with a low detection limit of 31 fg/mL and high specificity.
- * Additionally, the system allows for the encryption of textual information within the current signal responses, which can be translated into binary code, demonstrating the potential for molecular digitization.
Article Synopsis
- * The probe exhibits simultaneous fluorescence and scattering signals, allowing rapid (1 min) and specific detection of antibiotics like tetracycline and its variants, with low detection limits ranging from 15.31 nM to 28.30 nM.
- * Additionally, the research explores using the Eu/Zn-MOF in advanced applications like Boolean logic computing and information encryption, demonstrating potential for improved security and detection technologies in molecular sensors.
Article Synopsis
- The study explores charge transport mechanisms in glutathione-stabilized gold nanoclusters (GSH-Au NCs), focusing on the interplay between electron transfer and aggregation induction effects while sensing metal ions.
- A dual-channel sensing method combining fluorescence and second-order Rayleigh scattering is introduced, enabling high-throughput classification of metal ions like Pb, Ag, and Cu through distinctive signal behavior.
- The research demonstrates successful detection of multiple metal ions in real water samples, employing advanced analysis techniques and achieving a low detection limit, while also introducing a novel approach for information encoding using GSH-Au NCs.
Article Synopsis
- - A novel method for detecting folic acid (FA) was created using D-penicillamine-stabilized Ag/Cu alloy nanoclusters, which show a significant decrease in fluorescence when FA is present.
- - The detection range of this method is from 0.01 to 1200 μM, with a remarkably low limit of detection at 5.3 nM, and the quenching effect is linked to electron transfer from FA to the nanoclusters' ligands.
- - The sensor is highly selective; common amino acids and inorganic ions do not interfere with FA detection, and it proved effective in identifying FA in human serum and various tablets.
Human immunodeficiencey virus, type 1 (HIV-1) encodes three proteins, Nef, Vpu, and gp160, that down-modulate surface expression of the CD4 receptor during viral infection. In the present study, we have investigated the role of CD4 down-modulation in the HIV-1 infection cycle, primarily from the perspective of Vpu function. We report here that, like Nef, Vpu-mediated CD4 degradation modulates positively HIV-1 infectivity.
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