Publications by authors named "Yong-Qing Lu"

Gd and Yb elements have high chemical stability, which can stabilize the solid solution in ZrO. GdO and YbO have high melting points, and good oxidation resistance in extreme environments, stable chemical properties. Therefore, GdO and YbO were added to ZrO to stabilize oxides, improve the high temperature stability, and effectively decrease the thermal conductivity at high temperature.

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In recent years, the two issues of climate change including elevated CO etc., and resistance of transgenic Bt crops against non-target insect pests have received widespread attention. Elevated CO can affect the herbivorous insects.

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Study Hypothesis: What factors in mouse oocytes are involved in the ageing-related decline in oocyte quality?

Study Finding: The maternal effect gene Mater is involved in ageing-related oocyte quality decline in mice.

What Is Known Already: Premature loss of centromere cohesion is a hallmark of ageing-related oocyte quality decline; the maternal effect gene Mater (maternal antigen that embryos require, also known as Nlrp5) is required for preimplantation embryo development beyond the 2-cell stage, and mRNA expression of Mater decreases with maternal ageing.

Study Design, Samples/materials, Methods: Mater protein expression level in mature oocytes from 7 young (5-8 weeks old) to 7 old mice (41-68 weeks old) was compared by immunoblotting analysis.

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Pluripotent stem cells (PSCs) hold great promise in cell-based therapy, but the genomic instability seen in culture hampers their full application. A greater understanding of the factors that regulate genomic stability in PSCs could help address this issue. Here we describe the identification of Filia as a specific regulator of genomic stability in mouse embryonic stem cells (ESCs).

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