Publications by authors named "Yong-Qi Qiao"

Article Synopsis
  • About 10% of patients experience surgical-site infections (SSI) after radical gastrectomy for gastric cancer, prompting a study to identify risk factors associated with these infections.
  • The study involved 590 patients and revealed that factors such as being male, undergoing total gastrectomy, lower albumin levels post-surgery, and receiving total parenteral nutrition were significant risks for developing SSI.
  • The findings suggest that addressing post-operative nutrition and antibiotic use could help reduce the incidence of SSI in these patients.
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Three new saikosaponin analogs, comastomasaponins I-K (1-3), were isolated from the aerial portions of Comastomapedunculatum. The structures of these compounds were elucidated on the basis of spectroscopic data analysis, and their nitric oxide production inhibitory activity was evaluated invitro.

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Eight new triterpenoid saponins, the saikosaponin homologs comastomasaponins A-H (1-8), as well as a known triterpenoid (9) and eight known saponins (10-17) were isolated from the aerial portions of Comastoma pedunculatum. The structures of these compounds were elucidated spectroscopically, and their hepatoprotective activity and cytotoxic activity were evaluated against five human tumor cell lines in vitro. Compounds 1, 5-12, 14, 15, and 17 exhibited potent hepatoprotective activity, and compound 11 displayed cytotoxic activity against HCT-8, Bel-7402, BGC-825, A549, and A2780 human tumor cell lines.

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