Publications by authors named "Yong-Peng He"
HE4 as a biomarker for diagnosis of lung cancer: A meta-analysis.
Medicine (Baltimore)
September 2019
Article Synopsis
- The study aimed to evaluate the effectiveness of serum HE4 as a diagnostic tool for lung cancer, analyzing various research articles published before June 2017.
- A meta-analysis of 21 studies including nearly 2,000 cases indicated a pooled sensitivity of 73% and specificity of 86% for HE4 in lung cancer diagnosis, with varied results based on race and diagnostic methods.
- Findings suggest HE4 is particularly effective for small cell lung cancer, highlighting the need for further research to understand factors affecting diagnostic accuracy.
Angiotensin II (AngII) is an important factor that promotes the proliferation of cancer cells, whereas celastrol exhibits a significant antitumor activity in various cancer models. Whether celastrol can effectively suppress AngII mediated cell proliferation remains unknown. In this study, we studied the effect of celastrol on AngII-induced HepG2 cell proliferation and evaluated its underlying mechanism.
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