N’-(2-Hydroxybenzylidene)-3-Methylbenzohydrazide and its Copper(II) Complex: Syntheses, Characterization, Crystal Structures and Biological Activity.

The hydrazone compound N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) was prepared. With H2L and copper acetate a new copper complex [Cu(HL)(NCS)]·CH3OH was synthesized. Both the hydrazone and the copper complex were characterized by physico-chemical methods and single crystal X-ray diffraction techniques.

Synthesis, X-Ray Crystal Structure of Oxidovanadium(V) Complex Derived from 4-Bromo-N’-(2-hydroxybenzylidene) benzohydrazide with Catalytic Epoxidation Property.

A new oxidovanadium(V) complex, [VOL(OCH3)(CH3OH)], where H2L = 4-bromo-N'-(2-hydroxybenzylidene)benzohydrazide, has been synthesized and fully characterized on the basis of CHN elemental analysis, FT-IR, UV-Vis, 1H and 13C NMR spectroscopy. Structures of the free hydrazone and the complex were further characterized by single crystal X-ray diffraction, which indicates that the V atom in the complex adopts octahedral coordination, and the hydrazone ligand behaves as a tridentate ligand. The catalytic epoxidation property of the complex was investigated.

Syntheses, Crystal Structures and Catalytic Property of Oxidovanadium(V) Complexes Derived from Tridentate Hydrazone Ligands.

Two new ethyl maltolato coordinated mononuclear oxidovanadium(V) complexes [VOLa(emt)]·DMF (1) and [VOLb(emt)] (2), where H2La = N'-(4-bromo-2-hydroxybenzylidene)-3-hydroxybenzohydrazide, H2Lb = N'-(4-bromo-2-hydroxybenzylidene)benzohydrazide, Hemt = ethyl maltol, have been synthesized and characterized on the basis of CHN elemental analysis, FT-IR and UV-Vis spectroscopy and powder XRD analysis. Structures of the complexes were further characterized by single crystal X-ray diffraction, which indicated that the V atoms in the complexes adopt octahedral coordination. The hydrazones behave as NOO tridentate ligands.

Synthesis, inhibitory activity and molecular docking studies of two Cu(II) complexes against Helicobacter pylori urease.

Two mononuclear copper(II) complexes, [Cu(C(15)H(16)NO(2))(2)] (1) and [Cu(C(6)H(9)N(2)O(4))(2)·3H(2)O] (2·3H(2)O), were synthesised and structurally characterised by single-crystal X-ray analysis. The copper(II) atom adopts a square-planar environment in complex 1, while the geometry in 2·3H(2)O could be described as the distorted square pyramidal. Complexes 1 and 2·3H(2)O were evaluated for their inhibitory activities against Helicobacter pylori (H.

Bis(2-cyclo-hexyl-imino-methyl-4,6-dihydro-seleno-phenolato)cobalt(II) acetonitrile solvate.

In the title compound, [Co(C(13)H(16)NOSe(2))(2)]·CH(3)CN, the Co(II) atom is four-coordinated by two N,O-bidentate Schiff base ligands, resulting in a distorted tetra-hedral coordination for the metal ion.

Diaqua-bis[2-(4-bromo-phen-yl)acetato]bis-(N,N-dimethyl-pyridin-4-amine)copper(II).

In the title compound, [Cu(C(8)H(6)BrO(2))(2)(C(7)H(10)N(2))(2)(H(2)O)(2)], the Cu(II) atom (site symmetry ) adopts a Jahn-Teller-distorted trans-CuN(2)O(4) octa-hedral coordination, with the aqua O atoms in axially extended sites. An intra-molecular O-H⋯O hydrogen bond helps to establish the conformation and an inter-molecular O-H⋯O hydrogen bond is seen in the crystal packing.

2,4-Disulfanyl-6-[(E)-(2-sulfanylbenz-yl)imino-meth-yl]phenol.

In the title compound, C(14)H(13)NOS(3), the dihedral angle between the benzene rings is 73.26 (5)° and an intra-molecular O-H⋯N hydrogen bond occurs.

Bis{2-[(1H-pyrrol-2-yl)methyl-imino-meth-yl]phenolato-κN,O}zinc(II).

In the title compound, [Zn(C(12)H(11)N(2)O)(2)], the Zn(II) atom, lying on an inversion center, is coordinated by two O atoms and two N atoms from two salicylal Schiff base ligands in a distorted square-planar geometry. A three-dimensional network is formed by inter-molecular C-H⋯N hydrogen bonds and C-H⋯π contacts.

Aqua-bis(5-methyl-pyrazine-2-carboxyl-ato)zinc(II) trihydrate.

In the title compound, [Zn(C(6)H(5)N(2)O(2))(2)(H(2)O)]·3H(2)O, the Zn(II) centre is five-coordinated by two O,N-bidentate Schiff base ligands and one O atom from a water mol-ecule in a slightly distorted square-pyramidal geometry. In the crystal, the complex and uncoordinated water mol-ecules are linked by O-H⋯O, O-H⋯N and C-H⋯O hydrogen bonds, forming a three-dimensional network.

Effect of glabridin from Glycyrrhiza glabra on learning and memory in mice.

Glabridin was isolated from the roots of Glycyrrhiza glabra and its effects on cognitive functions and cholinesterase activity were investigated in mice. Glabridin (1, 2 and 4 mg kg (-1), P. O.

Ethyl 2-(4-chloro-phen-yl)-3-(3,5-dimethoxy-phen-oxy)acrylate.

The title compound, C(19)H(19)ClO(5), displays a dihedral angle of 74.7 (3)° between the mean planes of the 4-chloro-phenyl and phenol rings.

Ethyl 3-(2,4-difluoro-phen-oxy)-2-(4-methoxy-phen-yl)acrylate.

In the title mol-ecule, C(18)H(16)F(2)O(4), the two benzene rings form a dihedral angle of 55.2 (2)°. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into chains propagating along the c axis.

[Studies on flavonoids extraction technology from Glycyrrhiza inflata and their bacteriostatic activities].

Objective: To study the extraction technique for the flavonoids from Glycyrrhiza inflata and their bacteriostatic bioactivities.

Methods: It was investigated about comparison of extraction methods such as ultrasonic-assisted extraction (UAE), enzymatic extraction (EE), whisk extraction (WE) and repeat freeze-dissolve extraction (FDE). The UAE conditions were optimized by orthogonal array.