Combining pathological risk factors and T, N staging to optimize the assessment for risk stratification and prognostication in low-risk stage III colon cancer.

Background: This study aimed to investigate the combined pathological risk factors (PRFs) to stratify low-risk (pT1-3N1) stage III colon cancer (CC), providing a basis for individualized treatment in the future.

Patients And Methods: PRFs for low-risk stage III CC were identified using COX model. Low-risk stage III CC was risk-grouped combining with PRFs, and survival analysis were performed using Kaplan-Meier.

Construction and Validation of a Novel Prognosis Model in Colon Cancer Based on Cuproptosis-Related Long Non-Coding RNAs.

Colon cancer (CC) is one of the most common (6%) malignancies and leading cause of cancer-associated death (more than 0.5 million) worldwide, which demands reliable prognostic biomarkers. Cuproptosis is a novel modality of regulated cell death triggered by the accumulation of intracellular copper.

A Novel m7G-Related Gene Signature Predicts the Prognosis of Colon Cancer.

Colon cancer (CC), one of the most common malignancies worldwide, lacks an effective prognostic prediction biomarker. N7-methylguanosine (m7G) methylation is a common RNA modification type and has been proven to influence tumorigenesis. However, the correlation between m7G-related genes and CC remains unclear.

Prognostic Implications of Endoscopic Obstruction in Patients with Pathological Stage II Colon Cancers: a Single-Center Retrospective Cohort Study.

Background: The prognostic effect of endoscopic obstruction (eOB) on the survival of stage II colon cancer patients and the role of eOB in guiding postoperative adjuvant chemotherapy of stage II colon cancer are little known.

Methods: In this retrospective, single-center cohort study, patients who had undergone curative surgery and preoperative colonoscope for stage II colon carcinoma were included. The eOB was defined as severe luminal colon obstruction that prevented the standard colonoscope from passing beyond the tumor.

Risk factors for metachronous peritoneal carcinomatosis after radical resection for patients with nonmetastatic pT3-4 colon cancer.

Background: Patients with nonmetastatic pT3-4 colon cancers are prone to develop metachronous peritoneal carcinomatosis (mPC). Risk factors for mPC and the influence of mutant kirsten rat sarcoma viral oncogene (KRAS)/neuroblastoma rat sarcoma (NRAS)/v-raf murine sarcoma viral oncogene homolog B1 (BRAF) and DNA mismatch repair (MMR) status on mPC remain to be described in these patients.

Method: All enrolled patients were identified from the prospectively collected colorectal cancer database of a tertiary referral hospital between 2013 and 2018.

Risk factors for recurrence after bowel resection for Crohn's disease.

Background: Complications of Crohn's disease such as intestinal obstruction, fistula or perforation often need surgical treatment. Nearly 70%-80% patients with Crohn's disease would receive surgical treatment during the lifetime. However, surgical treatment is incurable for Crohn's disease.

Conversion is a risk factor for postoperative anastomotic leak in rectal cancer patients - A retrospective cohort study.

Aim: The impact of conversion from laparoscopic surgery to laparotomy on the development of anastomotic leak (AL) in rectal cancer patients following laparoscopic low anterior resection (LAR) with total mesorectal excision (TME) has not been evaluated. The aim of this study was to evaluate the impact of conversion on the risk of AL and develop a prediction nomogram for postoperative AL.

Methods: All rectal cancer patients following laparoscopic LAR with TME from January 2010 to October 2014 were enrolled in the primary cohort.

[Response of biocrust-soil system respiration to winter low temperature and simulated warming].

To study the effects of low temperature and simulated warming on respiration of biocrust-soil systems, intact soil columns covered by two dominant types of biocrusts (moss and algae-lichen crusts), were collected in a natural vegetation area in the southeast fringe of the Tengger Desert. Automated soil respiration system (Li-8150) was used to measure respiration rates in biocrust-soil systems under warming (by placing them in an open top chamber) and non-warming treatments in winter (from November 2015 to January 2016). During the whole observation period, soil respiration rates covered by moss crusts were significantly higher than those covered by algae-lichen crusts, which were -0.

[Nitrification of biological soil crusts and soil system during drought process and its response to temperature and moisture: A case study in the Shapotou region, Northwest China].

Two types of soil covered by biological soil crusts (BSCs) , i.e. moss and algae, and moving sand in the natural vegetation area at the southeast fringe of the Tengger Desert were collected intactly.

Dual Lewis Base Functionalization of Ionic Liquids for Highly Efficient and Selective Capture of H S.

Three dual Lewis base functionalized ionic liquids (DLB-ILs) tethered with both carboxyl and tertiary amine groups on their anions were designed for highly efficient and selective absorption of H S. It was found that the DLB-ILs could reversibly absorb 0.39-0.

[Expression of serum sICAM-1 in patients with primary hepatocellular carcinoma and its relationship with liver fibrosis].

Aim: To explore the clinical value of serum soluble intercellular adhesion molecule-1 (sICAM-1) in patients with primary hepatocellular carcinoma (PHC) and its relationship with liver fibrosis.

Methods: The serun sICAM-1, PC III, IV-C, LN and HA level of 45 cases of patients with PHC, 30 cases of benign tumor and 35 cases of healthy people were determined by ELISA, the relationship between sICAM-1 and liver fibrosis was analyzed.

Results: The serum sICAM-1, PC III, IV-C, LN and HA levels of the PHC group were significantly higher than that of the benign tumor group and normal control group, compared the difference was significant (P<0.

[Effects of incubation temperature and substrate humidity on embryonic development of Mauremys mutica].

Yellow pond turtle (Mauremys mutica) eggs were incubated in vermiculite under nine combinations of temperature and humidity, i. e., 25 degrees C and -12 kPa, 29 degrees C and -12 kPa, 33 degrees C and -12 kPa, 25 degrees C and -150 kPa, 29 degrees C and -150 kPa, 33 degrees C and -150 kPa, 25 degrees C and -300 kPa, 29 degrees C and -300 kPa, and 33 degrees C and -300 kPa, aimed to study the effects of incubation temperature and its interaction with substrate humidity on the embryonic development of M.