Publications by authors named "Yong-Kang Zhao"

Background: Bao-Gan-Xing-Jiu-Wan (BGXJW) is a clinical experience-based Chinese herbal formula. Its efficacy, pharmacological safety, targeted function, process quality, and other aspects have met the evaluation standards and the latest requirements of preparations. It could prevent and alleviate the symptoms of drunkenness and alcoholic liver injury clinically.

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Article Synopsis
  • The gut microbiota significantly influences human health and immunity, and its composition changes with aging, leading to inflammation and increased risk of diseases.* -
  • Plant polysaccharides, specifically Eucommiae polysaccharides (EPs), have shown potential in improving gut health by reducing harmful bacteria and promoting beneficial ones, but their effects on aging-related microbiota changes are not well understood.* -
  • Research on Drosophila indicates that EPs can extend lifespan, reduce age-related reactive oxygen species (ROS) levels, and help prevent gut dysfunction associated with aging, suggesting their potential as prebiotics for improved gut health in older populations.*
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Backgrounds: Drug induced liver injury (DILI) is sometimes similar to autoimmune hepatitis (AIH) in serology and histology. Clinicians empirically screened DILI with significant autoimmune characteristics to implement clinical intervention. We tried to characterize DILI with autoantibodies by metabolomics.

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