Renormalization-Group Evolution for the Three-Particle B-Meson Soft Function.

We determine for the first time the renormalization-group equation for the three-particle B-meson soft function dictating the nonperturbative strong interaction dynamics of the long-distance penguin contributions to the double radiative B-meson decays. The distinctive feature of the ultraviolet renormalization of this fundamental soft function consists in the pattern of mixing positive into negative support for an arbitrary initial condition. The exact solution to this integrodifferential evolution equation is then derived with the Laplace transform technique, allowing for the model-independent extraction of the asymptotic behavior at large and small partonic momenta.

Copper(ii)-catalyzed and acid-promoted highly regioselective oxidation of tautomerizable C(sp)-H bonds adjacent to 3,4-dihydroisoquinolines using air (O) as a clean oxidant.

A mild, efficient and eco-friendly method for the oxidation of 1-Bn-DHIQs to 1-Bz-DHIQs without concomitant excessive oxidation of 1-Bz-DHIQs to 1-Bz-IQs is very important for the syntheses of 1-Bz-DHIQ alkaloids and analogues. In this article, we developed a novel Cu(ii)-catalyzed and acid-promoted highly regioselective oxidation of tautomerizable C(sp)-H bonds adjacent to the C-1 positions of various 1-Bn-DHIQs. It was observed that when 0.

Novel Stereoselective Syntheses of (+)-Streptol and (-)-1-Streptol Starting from Naturally Abundant (-)-Shikimic Acid.

Novel highly stereoselective syntheses of (+)-streptol and (-)-1--streptol starting from naturally abundant (-)-shikimic acid were described in this article. (-)-Shikimic acid was first converted to the common key intermediate by 11 steps in 40% yield. It was then converted to (+)-streptol by three steps in 72% yield, and it was also converted to (-)-1--streptol by one step in 90% yield.

Enhancement role of host 12/15-lipoxygenase in melanoma progression.

12/15-Lipoxygenase (12/15-LOX) is a non-haeme iron-containing dioxygenase that forms 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) or 15(S)-HETE. Several biological mediators including cytokines, growth factors and lipid metabolites released during tumour cell-endothelial cell adhesion are associated with malignant tumour progression. Here we found that HETEs released from the host organ played a critical role in tumour metastasis.