[Precise application of Beichaihu and Nanchaihu in classical formulas].

To maintain the precision and stability of the efficacy of classical formulas, this study compared the origins and specifications of Bupleuri Radix and revealed the precise application regularity of Bupleurum chinense(Beichaihu) and Bupleurum scorzonerifolium(Nanchaihu) in classical formulas. The efficacy and indications of formulas with Bupleuri Radix as the sovereign drug in the Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun) were investigated. The difference in the efficacy of Bupleuri Radix as well as the differences in the chemical composition, and liver-protecting and lipid-lowering effects of the decoctions of Beichaihu and Nanchaihu were analyzed with LC-MS technology based on the CCl_4-induced liver injury model in mice and sodium oleate-induced HepG2 hyperlipidemia cell model.

[Interleukin-8 regulations of oral epithelial cells by porphyromonas gingivalis with different fimA genotypes].

Objective: The expression of heterogenic virulence properties depends on its clonal diversity. The aim of the study was to investigate the mechanism of interleukin-8 (IL-8) regulations of oral epithelial cells by challenge of Porphyromonas gingivalis (P. gingivalis) with different fimA genotypes, discuss the relation between fimA genotype and its pathogenicity.

[The distribution of fimA genotype of Porphyromonas gingivalis in chronic periodontitis patients].

Objective: To investigate the distribution of fimA genotype of P. gingivalis in chronic periodontitis patients.

Methods: Subgingival plaque samples were collected from 101 chronic periodontitis patients.

[A survey on knowledge and habits of oral health in freshmen of Sichuan University].

Objective: To investigate the oral health knowledge and habits of freshmen of Sichuan University and promote the prophylactic therapy of dental diseases in the university.

Methods: The table and the standard on oral health survey authorized by WHO were employed in this study.

Results: Only 13.

[Interleukin-1beta and IL-1 receptor antagonist levels in gingival crevicular fluid and their relationship to clinical indices of periodontitis].

Objective: To investigate Interleukin-1beta (IL-1beta) and IL-1 receptor antagonist (IL-1ra) concentrations in gingival crevicular fluid (GCF) of periodontally healthy teeth and to periodontitis teeth and to reveal their relationships to periodontal clinical indices.

Methods: Thirty GCF samples were harvested from periodontally healthy sites in which 15 samples were from periodontally healthy subjects and 15 GCF samples were from patients with chronic periodontitis, and 43 GCF samples (including 28 samples from BOP positive sites and 15 samples from BOP negative sites) were harvested from periodontitis sites of 33 patients with chronic periodontitis. Clinical indices (GI, PPD and CAL) were recorded for each tooth.