[Surgical outcomes of pediatric symptomatic epilepsy and their influencing factors].

Objective: To investigate the surgical outcomes of pediatric symptomatic epilepsy and the influencing factors for postoperative outcomes.

Methods: A cohort of 48 children with symptomatic epilepsy received surgical treatment from October 2004 to September 2008. The surgical outcomes were followed up.

[Expression of peroxisome proliferator-activated receptor-gamma in human pituitary adenomas and its correlation to tumor invasiveness].

Background & Objective: Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a nuclear transcription factor. Its ligant can inhibit proliferation and enhance differentiation of tumor cells, which plays crucial roles in metastasis and invasion of tumors. This study was to investigate the expression of PPARgamma in human pituitary adenomas and its clinical significance.

[Electrocorticography monitoring in microsurgical treatment of solitary cavernous angiomas].

Objective: To investigate the curative effect of electrocorticography (ECoG) monitoring in the microsurgical treatment of cavernous angiomas.

Methods: Clinical data of 71 patients with epileptogenic cavernous angiomas,who had been performed ECoG monitoring during the operation,were analyzed retrospectively.

Results: The foci of cavernous angiomas and epilepsy of the 71 patients were resected during the operation.

Expression of galectin-3 correlates with apoptosis in pituitary adenoma cells.

Objective: To investigate the expressions of Galectin-3 (Gal-3), Bcl-2 and Bax in human pituitary adenomas, and to explore the interrelation among them.

Methods: RT-PCR and immunohistochemistry were applied to detect the mRNA and protein expressions of Gal-3, Bcl-2 and Bax in surgically excised human pituitary adenoma tissues, including invasive and non-invasive pituitary adenomas, and the correlation analysis was performed.

Results: The Gal-3 and Bcl-2 expressions in the invasive pituitary group were significantly higher than those in the non-invasive group, and the expression of Bax had no significant difference between the two groups.

[Effect of different tidal volume ventilations on atelectasis in patients during general anesthesia by CT scan].

Objective: To investigate the effect of different tidal volume ventilations on the amount of atelectasis during general anesthesia.

Methods: Twenty adults, ASA physical status I and status II patients, who were scheduled for elective excision of intracranial lesion were randomly divided into 2 groups: Group TV (traditional tidal volume ventilation, 10 mL/kg) and Group LV (low tidal volume ventilation, 6 mL/kg). Atelectasis, as determined by CT and artery blood gas (ABG) analysis, was measured before the anesthesia, after the tracheal intubation, and at the end of the operation, respectively.

[Gamma knife treatment for pituitary prolactinomas].

Objective: To evaluate the outcome of gamma knife for prolactinomas.

Methods: Eighty-nine patients were treated by gamma knife and 51 were followed up. The dose to the tumor margin ranged from 18 Gy to 35 Gy (mean 26.

[Detection and clinical significance of urinary epidermal growth factor in brain tumor patients].

Objective: To investigate the clinical significance of urinary epidermal growth factor (EGF) in patients with brain tumors.

Methods: The levels of EGF in urine samples collected from 20 patients (9 low grade astrocytomas, 6 anaplastic astrocytomas, and 5 meningiomas) and 5 healthy individuals were determined. EGF levels were measured by radioimmunoassay technique.

[Gamma knife treatment for pituitary adenomas].

Objective: To evaluate the function and effect of Gamma knife radiosurgery (GKR) in controlling the tumor growth and improving endocrinological abnormality of pituitary adenomas.

Methods: Two hundred and twenty-eight cases of pituitary adenoma were treated with Leksell Gamma knife. 1.