Survey of the use of statistical methods in .

Objectives: This study aimed to describe recent patterns in the types of statistical test used in original articles that were published in .

Materials And Methods: Thirty-six original articles published in the in 2015 and 2016 were ascertained. The type of statistical test was identified by one researcher.

Epidemiology of Implant Mortality Disparity Among Intraoral Positions and Prosthesis Types.

Purpose: To examine the disparity of single-crown implant failure with a similar loss of the splinted prosthesis in differing anatomical locations while controlling for other demographic and clinical variables that may confound the relationship between prosthesis types and implant loss.

Materials And Methods: A multicenter retrospective cohort study was designed to include patients treated with dental implants from 2003 to 2014. The variables included age, sex, systemic disease, bone graft, implant placement date, position of dental implant, length of dental implant, diameter of dental implant, loading time, type of prosthesis, type of opposing occlusion, latest check date, and survival or loss of the dental implant.

Comparison of backbone dynamics of the type III antifreeze protein and antifreeze-like domain of human sialic acid synthase.

Antifreeze proteins (AFPs) are found in a variety of cold-adapted (psychrophilic) organisms to promote survival at subzero temperatures by binding to ice crystals and decreasing the freezing temperature of body fluids. The type III AFPs are small globular proteins that consist of one α-helix, three 3(10)-helices, and two β-strands. Sialic acids play important roles in a variety of biological functions, such as development, recognition, and cell adhesion and are synthesized by conserved enzymatic pathways that include sialic acid synthase (SAS).

NMR study of the Z-DNA binding mode and B-Z transition activity of the Zα domain of human ADAR1 when perturbed by mutation on the α3 helix and β-hairpin.

The Zα domains of human ADAR1 (ZαADAR1) bind to Z-DNA via interaction mediated by the α3-core and β-hairpin. Five residues in the α3 helix and four residues in the β-hairpin play important roles in Zα function, forming direct or water-mediated hydrogen bonds with DNA backbone phosphates or interacting hydrophobically with DNA bases. To understand the roles of these residues during B-Z transition of duplex DNA, we performed NMR experiments on complexes of various ZαADAR1 mutants with a 6-bp DNA duplex at various protein-to-DNA molar ratios.

Clinical statistics: five key statistical concepts for clinicians.

Statistics is the science of data. As the foundation of scientific knowledge, data refers to evidentiary facts from the nature of reality by human action, observation, or experiment. Clinicians should be aware of the conditions of good data to support the validity of clinical modalities in reading scientific articles, one of the resources to revise or update their clinical knowledge and skills.

NMR dynamics study of the Z-DNA binding domain of human ADAR1 bound to various DNA duplexes.

The Z-DNA binding domain of human ADAR1 (Zα(ADAR1)) preferentially binds Z-DNA rather than B-DNA with high binding affinity. Here, we have carried out chemical shift perturbation and backbone dynamics studies of Zα(ADAR1) in the free form and in complex with three DNA duplexes, d(CGCGCG)(2), d(CACGTG)(2), and d(CGTACG)(2). This study reveals that Zα(ADAR1) initially binds to d(CGCGCG)(2) through the distinct conformation, especially in the unusually flexible β1-loop-α2 region, from the d(CGCGCG)(2)-(Zα(ADAR1))(2) complex.

A 5-year retrospective clinical study of the Dentium implants.

Purpose: The aim of this retrospective study was to evaluate cumulative survival rate (CSR) of Implantium implants followed for 5 years and association between risk factors and the CSR.

Materials And Methods: A total of two hundred forty-nine Implantium Implants System (Dentium, Seoul, Korea) placed in ninety-five patients from 2004 to 2009 were investigated with several identified risk factors (sex, systemic disease, smoking, alchohol, reason of tooth loss, length, arch (maxilla or mandible), replace tooth type (incisor, canine, premolar or molar) Kennedy classification, prosthodontic type, prosthodontic design, opposite dentition, abutment type, occlusal material, occlusal unit, splint to tooth, cantilever, other surgery). Clinical examination (mobility, percussion, screw loosening, discomfort, etc.

Immediate restoration with ti-unite implants: practice-based evidence compared with animal study outcomes.

Purpose: Clinicians often do not have the benefit of adequate safety or clinical data when evaluating the merit of either newly marketed implant devices or novel clinical procedures. This has been the case for dental implants following the initial documentation of their safety and efficacy and is demonstrated in the evolution of immediate load application. Following demonstration of safety and successful application of an implant in an animal study prior to its market release, this report provides the clinical outcomes for the first 100 Ti-Unite implants provided to 24 patients in a clinical practice over 9 years.

Heat transfer to the implant-bone interface during preparation of a zirconia/alumina abutment.

Purpose: Excessive heat at the implant-bone interface may compromise osseointegration. This study examined the heat generated at the implant surface during preparation of a zirconia/alumina abutment in vitro.

Materials And Methods: Sixty zirconia/alumina abutments were randomized into 12 experimental groups.

Evaluation of peri-implant tissue in nonsubmerged dental implants: a multicenter retrospective study.

Objectives: The objective of this study was to evaluate the peri-implant's hard and soft tissue response associated with the 1-stage, nonsubmerged, endosseous dental implant.

Study Design: A multicenter retrospective clinical evaluation was performed on 339 nonsubmerged implants placed in 108 patients at 5 clinical centers between January 2003 and December 2007.

Results: After a mean follow-up period of 30 months, the mean crestal bone resorption in 339 implants was 0.

The effect of several dentin desensitizers on shear bond strength of adhesive resin luting cement using self-etching primer.

Objectives: Dentin desensitizers can inhibit the bonding between dentin and resin cements. This study examined the effect of the previous application of desensitizers on the shear bond strength of one resin cement using self-etching primer to dentin.

Materials And Methods: One hundred and twenty-five dentin exposed teeth were randomly assigned to four experimental groups and one control group of 25 teeth each.

Clinical decision-making practices among a subset of North American prosthodontists.

The aim of this study was to determine the decision-making practices of a subset of North American prosthodontists. A survey was administered to assess practitioner views regarding the relative importance of practitioner, patient, and patient family beliefs and preferences during treatment planning of the edentulous patient. In responses to abstract questions, practitioners appeared to endorse a blending of patient and practitioner beliefs and preferences when treatment planning.

Retrospective multicenter cohort study of the clinical performance of 2-stage implants in South Korean populations.

Purpose: To evaluate long-term follow-up clinical performance of dental implants in use in South Korean populations.

Materials And Methods: A retrospective multicenter cohort study design was used to collect long-term follow-up clinical data from dental records of 224 patients treated with 767 2-stage endosseous implants at Ajou University Medical Center and Bundang Jesaeng Hospital in South Korea from June 1996 through December 2003. Exposure variables such as gender, systemic disease, location, implant length, implant diameter, prosthesis type, opposing occlusion type, and date of implant placement were collected.

Cyclic loading of implant-supported prostheses: comparison of gaps at the prosthetic-abutment interface when cycled abutments are replaced with as-manufactured abutments.

Statement Of Problem: Implant-supported prostheses are mechanically connected to implants. When this connection is a screw joint, it is likely that the fit will be imperfect. Previous studies demonstrate that deformation can occur at the interface between the prosthesis and implant following cyclic loading.

Osseointegrated craniofacial implants in the rehabilitation of orbital defects: an update of a retrospective experience in the United States.

Statement Of Problem: Since their introduction, craniofacial implants have been used in prosthetic rehabilitation of facial defects. The literature, however, indicates marked variability in outcomes using implants for the retention of orbital prostheses.

Purpose: A multicenter report updating the experience in the United States with the use of craniofacial implants for prosthetic rehabilitation of orbital defects is presented.

Comparison of dental implant systems: quality of clinical evidence and prediction of 5-year survival.

Purpose: This literature review was conducted to evaluate the quality of current evidence of clinical performance provided by American Dental Association-certified dental implant manufacturers and manufacturers with strong market penetration in the United States. The study also compared the clinical performance of different dental implant systems.

Materials And Methods: A letter was sent to 6 implant manufacturers requesting 10 references each that validated the manufacturer's implant system in a variety of clinical applications.

Cross-sectional study of the factors that influence radiographic magnification of implant diameter and length.

Purpose: To study the factors that influence radiographic magnification of implant diameter and length.

Materials And Methods: The dental records and panoramic radiographs of 80 patients with 210 dental implants treated with implant-supported prostheses at Bundang Jesaeng Hospital in South Korea from January 2000 through February 2003 were reviewed. The panoramic radiographs were developed under standardized conditions.

Methods for comparing the results of different studies.

The reader of oral and maxillofacial implant literature is challenged to be cognizant of the quality of clinical research data. The large variety of possible study designs utilized by clinical researchers requires the reader to have a fundamental awareness of the advantages, disadvantages, and limitations of commonly utilized study designs. This article aims to provide the reader with information to make an informed decision regarding the quality of a clinical research paper, so that he or she can judge whether the information presented in any given manuscript was obtained in a manner that truly minimizes bias, in the form of systematic or random errors, and whether it warrants serious consideration for clinical decision making.

Retrospective cohort study of the clinical performance of 1-stage dental implants.

Purpose: To evaluate long-term clinical performance of 1-stage dental implant prostheses at a single clinic, emphasizing clinical and demographic characteristics that affect implant survival.

Materials And Methods: Dental records of all 308 patients (674 implants) treated with 1-stage implants at Mayo Clinic from October 1993 through May 2000 were reviewed from implant placement to last visit. Exposure and outcome variables affecting performance were collected separately to control bias in the data collection process.

Survey of implant experience by prosthodontists in the United States.

Purpose: The paper presents results of a survey of members of the American College of Prosthodontists (ACP) conducted to determine experiences and practices with dental implants.

Materials And Methods: Preliminary survey questions regarding the prosthetic and surgical use of dental implants were developed. The master list of questions was distributed to communities of interest to establish the most pertinent items of interest.