Publications by authors named "Yong-Fei Zhou"
Article Synopsis
- The liver is essential for detoxifying the body, and liver damage can occur if it becomes overwhelmed, highlighting the need for effective liver health maintenance.
- Xiaobugan Decoction (XBGD), a traditional Chinese medicine, is used to support liver health, but its protective effects against liver injury were not well understood until this study.
- The research found that XBGD helps protect liver cells and reduce liver injury by improving key enzyme levels, decreasing oxidative stress, and lowering inflammation in both cellular and mouse models.
Portulaca oleracea L. (purslane) is a vegetable that contains a variety of active compounds with nutritional properties and has the potential to treat ulcerative colitis (UC). However, the mechanisms underlying the effects of Portulaca oleracea L.
View Article and Find Full Text PDFPolysaccharides are one of the most abundant and active components of Lysimachia christinae (L. christinae), which is widely adopted for attenuating abnormal cholesterol metabolism; however, its mechanism of action remains unclear. Therefore, we fed a natural polysaccharide (NP) purified from L.
View Article and Find Full Text PDFHepatitis E is an emerging zoonotic disease, posing a severe threat to public health in the world. Since there are no specific treatments available for HEV infection, it is crucial to develop vaccine to prevent this infection. In this study, the truncated ORF2 encoded protein of 439aa∼617aa (HEV3-179) from HEV CCJD-517 isolates was expressed as VLPs in E.
View Article and Find Full Text PDFArticle Synopsis
- - The study focused on enhancing the sensitivity of A375·S2 cells to interleukin-1 (IL-1) by co-expressing the IL-1 receptor (IL-1R1) and its co-receptor (IL-1R1AcP) genes, demonstrating successful expression using laser scanning confocal microscopy.
- - Quantitative PCR (qPCR) analysis showed a favorable gene ratio of 4.57:1, and after co-transfection, both qPCR and Western blotting indicated a significant increase in protein levels.
- - MTS assays confirmed that the co-transfected A375·S2 cells exhibited noticeably heightened sensitivity to IL-1β, suggesting the potential for this cell
COVID-19 is an emerging disease that poses a severe threat to global public health. As such, there is an urgent demand for vaccines against SARS-CoV-2, the virus that causes COVID-19. Here, we describe a virus-like nanoparticle candidate vaccine against SARS-CoV-2 produced by an expression system.
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