Synopsis of recent research by authors named "Yong-Fei Zhao"
- Yong-fei Zhao's research primarily focuses on the neuroprotective effects of agomelatine and its potential role in treating neurodegenerative diseases, particularly Alzheimer's and Parkinson's diseases, by addressing issues such as amyloid plaque deposition, tau phosphorylation, and neuroinflammation.
- His studies highlight the role of aging in neuroinflammatory processes and the modulation of microglial phenotypes, indicating that age-related changes contribute significantly to the pathogenesis of neurodegenerative disorders, including Parkinson's disease.
- Zhao's investigations into signaling pathways, particularly the Rho kinase pathway, suggest that targeting these pathways through pharmacological interventions may offer new therapeutic strategies for neuroprotection and management of symptoms in conditions such as multiple sclerosis and experimental autoimmune encephalomyelitis.