Complement factor I knockdown inhibits colon cancer development by affecting Wnt/β-catenin/c-Myc signaling pathway and glycolysis.

Background: Colon cancer (CC) occurrence and progression are considerably influenced by the tumor microenvironment. However, the exact underlying regulatory mechanisms remain unclear.

Aim: To investigate immune infiltration-related differentially expressed genes (DEGs) in CC and specifically explored the role and potential molecular mechanisms of complement factor I (CFI).

Investigation of the mechanical and transport properties of InGeX (X = S, Se and Te) monolayers using density functional theory and machine learning.

Recently, novel 2D InGeTe has been successfully synthesized and attracted attention due to its excellent properties. In this study, we investigated the mechanical properties and transport behavior of InGeX (X = S, Se and Te) monolayers using density functional theory (DFT) and machine learning (ML). The key physical parameters related to mechanical properties, including Poisson's ratio, elastic modulus, tensile strength and critical strain, were revealed.

A first-principles study of 1D and 2D Cnanostructures: strain effects on band alignments and carrier mobility.

In the breakthrough progress made in the latest experiment Hou(2022507), 2DC60polymer was exfoliated from the quasi-hexagonal bulk crystals. BulkC60polymer with quasi-tetragonal phase was found to easily form 1D fullerene structure withC60molecules connected by C=C. Inspired by the experiment, we investigate the strain behaviors of 1D and 2DC60polymers by first-principles calculations.